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Risk of Pneumonia in Intubated Patients in Emergency Situations

Risk of Pneumonia in Intubated Patients in Emergency Situations

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07439146
Acronym
PNEUMIOT
Enrollment
600
Registered
2026-02-27
Start date
2026-02-09
Completion date
2026-12-31
Last updated
2026-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orotracheal Intubation, Pneumonia

Keywords

Orotracheal intubation in emergency, Pneumonia

Brief summary

Orotracheal intubation in emergency medicine is a vital procedure for ensuring adequate oxygenation and ventilation in patients with respiratory distress or in shock. However, this procedure exposes patients to complications such as pneumonia. In the matter of fact, the urgency of the procedure means that it is not possible to wait until the patient's stomach is empty. Pneumonia significantly increase patient morbidity and mortality. Therapeutic management must be early and appropriate to improve the patient's prognosis. The aim of this study is to compare the rate of pneumonia occurring in patients intubated in emergency situations with that in patients intubated in non-emergency situations in all 2024. Health data will only collected from patient's medical records.

Interventions

None listed

Sponsors

University Hospital, Clermont-Ferrand
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult man or woman * Emergency and non-emergency intubated patient in 2024 * Patient hospitalized in intensive care following intubation in 2024

Exclusion criteria

* Patient under guardianship, curatorship or safeguard of justice * Pregnant woman * Refusal to participate

Design outcomes

Primary

MeasureTime frameDescription
Pneumonia rate in 48 hours after the start of orotracheal intubation.Hour 48Rate of pneumonia occuring within 48 hours of the start of orotracheal intubation.

Secondary

MeasureTime frameDescription
Pneumonia rate occuring 48 hours after the start of orotracheal intubation.3 monthsRate of pneumonia occuring more than 48 hours after the start of orotracheal intubation.
Duration of mechanical ventilationUp to the end of mechanical ventilation (assessed up to 1 month)Duration of mechanical ventilation
Duration of stay in intensive careUp to intensive care discharge (assessed up to 1 month)Duration of stay in intensive care
Duration of hospital stayUp to hospital discharge (assessed up to 3 months)Duration of hospital stay
Mortality rateInclusion + 1 yearMortality rate
Type of bacteria responsible for pneumoniaThe day of the diagnosis of pneumonia (assessed up to 1 month)The bacterial species responsible for pneumonia will be identified using biological samples (blood, urine, bronchial secretions) taken from patients in both groups. The identification of bacterial species will be carried out in the laboratory.
Type of antibiotic administered for pneumoniaUp to the last day of antibiotic treatment (assessed up to 3 months)Type of antibiotic administered for pneumonia in each group
Antibiotic doses administered for pneumoniaUp to the last day of antibiotic treatment (assessed up to 3 months)Comparison of antibiotic doses in g or mg administered in each group
Duration of antibiotic treament for pneumoniaUp to the last day of antibiotic treatment (assessed up to 3 months)Duration of antibiotic treament for pneumonia in each group

Countries

France

Contacts

CONTACTLise Laclautre
promo_interne_drci@chu-clermontferrand.fr334.73.754.963
PRINCIPAL_INVESTIGATORJean-Baptiste BOUILLON-MINOIS

University Hospital, Clermont-Ferrand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026