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High-Load, Low-Load, and Passive Blood Flow Restriction in Competitive Sprinters

Comparative Effects of High-Load, Low-Load, and Passive Blood Flow Restriction Training on Strength and Sprint Performance in Competitive Sprinters

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07438535
Enrollment
18
Registered
2026-02-27
Start date
2025-12-01
Completion date
2026-09-01
Last updated
2026-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Flow Restriction

Keywords

Blood Flow Restriction, Competitive Sprinters, High-Load, Low-Load, Passive Blood Flow Restriction

Brief summary

This randomized clinical trial will include competitive male and female sprinters aged 16-30 years, recruited through purposive sampling. Participants will be randomly assigned to one of three groups: (A) HL-BFR (70-85% 1RM with BFR during sets), (B) LL-BFR (20-30% 1RM with BFR), or (C) Passive BFR (BFR applied between sets). The intervention will consist of a 6-week sprint-specific resistance training program performed thrice weekly, incorporating resisted sprints, barbell step-ups, hip thrusts, Nordic curls, and bounding exercises. Strength will be measured using 1RM testing, explosive power through countermovement and standing broad jumps, and sprint performance via 10m, 30m, and 100m timed sprints. Subjective exertion will be tracked using the sRPE scale. The study aims to determine whether HL-BFR, LL-BFR, or passive BFR produces superior improvements in sprint performance and neuromuscular strength. It is hypothesized that HL-BFR may yield greater adaptations due to combined mechanical and metabolic stress, though LL-BFR and passive BFR may offer practical, low-impact alternatives.

Detailed description

Blood Flow Restriction (BFR) training characterized by applying external pressure to occlude venous return during exercise has gained prominence in both rehabilitation and athletic conditioning due to its ability to stimulate muscle hypertrophy and strength gains with lighter mechanical loads. The physiological basis includes metabolic accumulation, cellular swelling, and increased motor unit recruitment, mimicking high-intensity training effects even with low loads . Elite sprint performance demands a finely tuned combination of explosive strength, neuromuscular power, and sprint-specific endurance across different phases of the race (acceleration, maximal velocity, deceleration). While high-load resistance training (≥ 70% 1RM) has long been the gold standard for developing muscular strength and power , blood flow restriction (BFR) training-particularly in low-load protocols (20-40% 1RM)-has emerged as a low-stress alternative capable of eliciting comparable hypertrophy and strength gains. A growing body of literature now highlights the capacity of both high- and low-load BFR training to improve explosive performance metrics, such as vertical jump, sprint speed, and rate of force development. A systematic review found that athletes undergoing BFR training experienced small to moderate yet significant improvements in jumps (SMD ≈ 0.36), sprints (SMD ≈ 0.54), and power output (SMD ≈ 0.72), surpassing traditional resistance training outcomes. High-load resistance training (≥ 70 % 1RM) is the established standard for enhancing neuromuscular strength and power. Recent investigations have examined adding BFR to high-load protocols (high-load BFR), aiming to amplify metabolic stress and post-activation performance enhancement. Though the evidence is mixed-a systematic review of ≥ 60 % 1RM BFR protocols concluded that only some studies showed additional strength or hypertrophy benefits compared to non-BFR controls emerging data suggest that high-load BFR may offer acute increases in lifting velocity and small improvements in jump and sprint outcomes. Among BFR strategies, low-load BFR (LL-BFR)-typically at 20-40% of one-repetition maximum (1RM)-has the most robust evidence base. Systematic reviews demonstrate that LL-BFR training can induce similar muscle hypertrophy and near-equivalent strength improvements compared to traditional high-load training . These benefits, coupled with lower mechanical stress, have made LL-BFR a preferred method in both clinical and performance settings. Meta-analyses report that while maximum strength gains are slightly lower than high-load training, power, jump, and sprint performance show no significant differences between low-load BFR and high-load resistance training.

Interventions

OTHERHigh-Load Blood Flow Restriction Training (HL-BFR)

In the High-Load BFR group, participants will perform resistance exercises at 70-85% of one-repetition maximum (1RM) with BFR applied during exercise sets.

OTHERLow-Load Blood Flow Restriction Training (LL-BFR)

In the Low-Load BFR group, participants will perform resistance exercises at 20-30% of one-repetition maximum (1RM) with BFR applied during exercise sets.

OTHERPassive Blood Flow Restriction Training (PBFR)

In the Passive BFR group, participants will perform resistance exercises at 70-85% of one-repetition maximum (1RM) with BFR applied only during rest intervals between sets.

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 16-30 years * Competitive sprinters with at least 2 years of sprint-specific training * Healthy individuals without cardiovascular, metabolic, musculoskeletal, or neurological disorders * Willingness to participate in a 6-week training program

Exclusion criteria

* Pregnancy or lactation * Cardiovascular, vascular, pulmonary, renal or metabolic disorders * Uncontrolled hypertension * Recent significant weight loss * Use of performance-enhancing drugs within past 2 months * Any medical condition preventing safe participation

Design outcomes

Primary

MeasureTime frameDescription
Lower Limb Muscle Strength (1RM Test)Baseline (Week 0) and Post-Intervention (Week 6)Maximum voluntary strength of lower limb muscles will be assessed using one repetition maximum (1RM) testing protocol for resistance training exercises.

Secondary

MeasureTime frameDescription
Vertical Jump HeightBaseline (Week 0) and Post-Intervention (Week 6)Explosive lower limb power will be assessed using vertical jump performance test measured in centimeters.
10-Meter Sprint TimeBaseline (Week 0) and Post-Intervention (Week 6)Sprint performance over short distance will be measured using timing gates in seconds.
30-Meter Sprint TimeBaseline (Week 0) and Post-Intervention (Week 6)Sprint acceleration and performance will be measured using electronic timing system in seconds.
100-Meter Sprint TimeBaseline (Week 0) and Post-Intervention (Week 6)Overall sprint performance will be assessed using timing system in seconds.
Participant-reported exertion during training sessions using Borg CR-10 Scale.Throughout Intervention Period (Week 1-6)Participant-reported exertion during training sessions using Borg CR-10 Scale.

Countries

Pakistan

Contacts

CONTACTDanish Hassan, PhD
danish.hassan009@gmail.com+92 345 7946009
PRINCIPAL_INVESTIGATORMuhammad Mubarak Janjua, MS PT

Riphah International University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026