Collection of Demographic, Clinical, and Instrumental Data of Patients With Peripheral Neuropathy Including Neurological Examination Data, Peripheral Nerve Conduction Analysis, and Nerve Electromyography and Ultrasound).

An Observational Prospective Study on Patients With Peripheral Neuropathies Explored With a Combined Clinical, Neurophysiological and Nerve Ultrasound Approach- REG-NP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07437989

Acronym

REG-NP

Enrollment

4000

Registered

2026-02-27

Start date

2025-02-23

Completion date

2035-02-01

Last updated

2026-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathy

Keywords

ultrasound, peripheral nervous system, Neurological, Electrodiagnostic, Neuromuscolar ultrasound

Brief summary

The study involves recording personal, clinical, and instrumental information. The acquisition of the above-mentioned personal and clinical information will be carried out in conjunction with the usual follow-up visits scheduled as part of normal clinical practice. At the end of the study, a statistical analysis of the data will be carried out.

Detailed description

Patients will be asked to participate in the prospective observational study after being fully informed of its objectives and how they will be pursued. Patient compliance is made official by signing the informed consent form. Patients will then undergo nerve conduction tests and electromyography, as appropriate, and ultrasound evaluation as per clinical practice. Prior to the above diagnostic investigations, patients will perform a neurological examination to assess the distribution and severity of neuropat

Interventions

OTHERperipheral neuropathies

the neurophysiological study aimed at studying the function of nerves and nerve ultrasound to evaluate its morphological appearance will be performed. Depending on the outcome of the tests carried out, further blood tests will be ordered to identify the causes of neuropathy and identify the most effective treatment where available.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Adult patients (age ≧ 18 years old) able to give consent 2. Diagnosis of peripheral nerve disorder

Exclusion criteria

1\. The patient is unable to consent for him/herself

Design outcomes

Primary

Measure	Time frame	Description
record of all diagnosed peripheral neuropathies	through study completion, an average of 1 year	The primary objective of the study is to make a record of all diagnosed peripheral neuropathies that systematically includes and collects demographic and clinical data (including data on diagnostic methods of an electrophysiological, imaging and laboratory nature) most relevant for the diagnostic and prognostic definition of such diseases.

Secondary

Measure	Time frame
assess the additional role of ultrasound in the diagnosis of diseases of the peripheral nervous system	through study completion, an average of 1 year
Identifying ultrasound parameters of disease severity and/or treatment response	through study completion, an average of 1 year

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026