Gingival Recession
Conditions
Brief summary
The study aimed to evaluate the effect of Hyaluronic Acid-based gel use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient satisfaction, analyzed at baseline and 6 months.
Detailed description
The aim of this study is to evaluate the effect of HA use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient satisfaction, analyzed at baseline and 6 months. This split-mouth study included 20 patients (9 males, 11 females) with a mean age of 42.10±9.46 years who were diagnosed with bilateral RT1 gingival recession in the maxilla. The right and left defect areas of the 20 patients were randomly assigned to two groups. The control group received CAF (n=20), and the test group received CAF+HA (n=20). Pre-treatment plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), vertical recession depth (VRD), horizontal recession width (HRW), gingival thickness (GT), attached gingival (AG), and keratinized gingival width (KGW) were recorded. Additionally, a satisfaction analysis was conducted, including patient-based comfort (PBC), aesthetic (PEA), and sensitivity (PHS) scores. During the operation, a 0.8% HA gel was applied to the defect areas in the test group, in addition to CAF, while saline was applied to the control group, also in addition to CAF. Pain, bleeding, and edema scores, as well as the amount of painkillers, were recorded during the 9-day postoperative period. Clinical parameter measurements and patient satisfaction analyses were repeated 6 months after surgical treatment.
Interventions
DRUGHyaluronic acid
0.8% hyaluronic acid gel (Gengigel Oral Forte Gel, Ricefarma, Milan, Italy)
OTHERSteril saline solution
Mix 8 teaspoons of salt into 4 L of distilled water
Sponsors
Ordu University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Double-sided type 1 gingival recession * No inflammation
Exclusion criteria
* active periodontal disease * smokers * pregnant and breastfeeding women * individuals with unilateral GR
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complete root coverage | 6 months postsurgery | for evaluating rate of complete root coverage |
| Mean root coverage | 6 months postsurgery | for evaluating rate of mean root coverage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Plaque Index | Baseline | to assess plaque accumulation |
| Gingival Index | Baseline | for evaluating gingival inflammation |
| Gingival index | 6 montsh post surgery | for evaluating gingival inflammation |
| Probing pocket depth | Baseline | for measuring disease severity |
| Clinical attachment level | Baseline | Clinical attachment level (CAL) is calculated by adding or subtracting probing depth (PD) and gingival recession (GR). The formula is CAL = PD + GR. CAL is measured in millimeters. |
| Vertical recession depth | Baseline | for evaluating gingival recession depth |
| Horizontal gingival recession | Baseline | for evaluating gingival recession depth |
| Attached gingival width | Baseline | for evaluating attached gingival width |
| Keratinized gingival width | Baseline | for evaluating keratinized gingival width |
| Gingival thickness | Baseline | for evaluating gingival thickness |
| Patient comfort score | Baseline | Patient satisfaction was assessed using a visual analog scale (VAS). "unbearable discomfort (score 0)" to "no discomfort (score 10)". |
| Patient aesthetic score | Baseline | Poor-unexpected aesthetics (score 0) → beautiful-perfect aesthetics (score 10) using VAS scale |
| Patient sensitivity score | Baseline | painless-discomfort no (score 0) → unbearable pain (score 10) using VAS scale |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORFigen Öngöz Dede, Prof
Ordu Universitesi
Outcome results
None listed