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Vision Therapy Outcomes in Amblyopia: Linking Brain Plasticity With Visual Perceptual Skills

Correlation of Vision Therapy With Visual-Cognitive Skills and Therapeutic Outcomes in Amblyopia: Linking Brain Plasticity With Visual Perceptual Skills

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07437807
Enrollment
38
Registered
2026-02-27
Start date
2024-06-12
Completion date
2025-09-30
Last updated
2026-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amblyopia

Keywords

Amblyopia, Vision Therapy, Visual Perceptual Skills, Visual-Cognitive Skills, Neuroplasticity

Brief summary

The primary objective of this study is to evaluate the effects of a personalized vision therapy programme tailored to baseline visual-cognitive abilities in treatment-resistant amblyopia. In addition to testing the hypothesis that rehabilitation protocols targeting amblyopia related visual-perceptual and visual-cognitive skills. Spesific aims of this study are: 1. to identify which visual perceptual skills are most significantly impaired sen patients with amblyopia. 2. to evaluate whether interventions are targeting fundamental visual perceptual skills are associated with improvements in higher-order visual perceptual skills. 3. to determine whether vision therapy tailored to individual neuro-visual impairments associated with improvements in binocular function, including streopsis and overall visual perceptual performance. 4. to ases whether baseline neuro-visual perceptual performance predicts the response to vision therapy in patients with amblyopia.

Interventions

DIAGNOSTIC_TESTMotor Free Perception Vision Test

The Motor-Free Visual Perception Test-3 (MVPT-3) represents a significant methodological iteration in the assessment of non-motor visual processing, specifically validated for individuals ranging from 4 to 95 years of age. In pediatric and adolescent contexts (under 18), the MVPT-3 is utilized to isolate cognitive visual-perceptual skills-such as spatial relationships, visual discrimination, figure-ground, and visual closure-from fine motor coordination, which may still be developing or impaired. The test consists of 65 items arranged in a horizontal format to accommodate individuals with hemispatial neglect or limited field of vision. For younger examinees, the assessment is particularly vital for identifying perceptual deficits that may impede academic performance, such as reading fluency or mathematical reasoning, without the results being skewed by the child's handwriting or drawing abilities. By providing age-adjusted normative data, the MVPT-3 allows clinicians to derive standard

Sponsors

Okan University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
4 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Ambylopia patient * Minimal response to traditional treatments * Ages between 4-18 * Receiving personalized vision therapy * Taking the TVPS-3 at least 2 times

Exclusion criteria

* Responsive to treatment * Discontinued vision therapy

Design outcomes

Primary

MeasureTime frame
The Correlation Between Vision Therapy and Visual Cognitive Skills and It's Therapeutic Results in Amblyopia: Associating with Brain Plasticity and Visual Perceptual SkillsFrom June 2024 to June 2025

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 11, 2026