Cardiac Amyloidosis, Chest Pain
Conditions
Brief summary
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.
Interventions
OTHERScreening thourgh examinations including bonescintigraphy
Clinical examination, blood samples, echo, bone scintigraphy
Sponsors
Rigshospitalet, Denmark
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
No signs of CAD through Rb-PET and/or CT coronary arteriogram
Exclusion criteria
Previous history of amyloidosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of ATTR-CA in patients experiencing chest pain | Up to 4 weeks |
Countries
Denmark
Contacts
CONTACTNavid Noory, MD
Outcome results
None listed