Gastric Cancer
Conditions
Keywords
gastrectomy, palliative, bypass
Brief summary
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to share in the trial. The main question is what is the better for management for obstructed gastric cancer; palliative resection or palliative bypass? We hypothesized that resection is better. patients will be divided into two groups. the primary outcome measure will be the relief of obstruction
Interventions
PROCEDUREpalliative gastric resection
distal, subtotal or total gastrectomy with gastro-jejunostomy or eosphago-jejunostomy will be done
PROCEDUREpalliative bypass
palliative gastro-jejunostomy or eosphago-jejunostomy will be done
Sponsors
Zagazig University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* emergency obstructed gastric cancer patients
Exclusion criteria
* non obstructed gastric cancer patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| upper gastrointestinal symptoms | from one day to two weeks after surgery | upper gastrointestinal symptoms will be evaluated after surgery by Rhodes Index questionnaire. It is a validated, self-report instrument used to measure the intensity, frequency, and distress of upper gastrointestinal symptoms. The scale measures three main areas: nausea (frequency, duration, distress), vomiting (amount, frequency, distress), and retching (frequency, distress). It utilizes a 5-point Likert scale (0-4) to quantify the severity of these symptoms. 0 is the least amount of distress and 4 is the most distress. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| anastmotic leak | from day one to two weeks after surgery. | anastmotic site leakage will be assessed by abnormal discharge in the drain calculated in cc. |
| ICU admission | from day one to two weeks after surgery | the need of ICU admission will be evaluated by (yes or No) |
| wound infection | from day one to one month after surgery | wound infection will be identified by presence of pus in the dressing and positive culture and sensitivity test |
| mortality | from one day to one month after surgery | follow up of patient after surgery (died or not) |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORReham Zakaria, M.D
Zagazig University, Egypt
Outcome results
None listed