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İnvestigation of the Effect of Neck Endurance on Swallowing and Directional Coordination in Head and Neck Cancer Patients

İnvestigation of the Effect of Neck Endurance on Swallowing and Directional Coordination in Head and Neck Cancer Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07434245
Enrollment
28
Registered
2026-02-25
Start date
2021-11-01
Completion date
2022-05-01
Last updated
2026-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Cancer, Neck Muscle Issue, Respiratory Function, Swallowing Disorder

Keywords

Neck Endurance, Neck ROM, İntraoral Pressure, Respiratory Assessment, Swallowing Assessment, Head and Neck Cancer

Brief summary

In the study, it was aimed to evaluate the relationship between dysphagia, which is one of the treatment complications, and the variables of respiratory performance, intraoral pressure and neck endura, and to look at the future work and rehabilitation methods of these evaluation outcomes from a different parameter.

Detailed description

Head and neck cancers; oral cancers, pharyngeal cancers, laryngeal cancers, salivary gland cancers, and cancers involving the skin of the head and neck region. Head and neck cancer treatment options include surgery, radiotherapy, and chemotherapy. Dysphagia, that is, difficulty in swallowing, is a symptom that affects the quality of life, which is often neglected in patients with head and neck cancer. 40% of patients suffer from dysphagia during and after treatment. Dysphagia causes serious complications such as aspiration, malnutrition and even death, in addition to causing increased health expenditures with a decrease in the quality of life. Swallowing and respiration are two vital functions coordinated with each other, ensuring coordination is vital. When the respiratory-swallowing relationship was examined in HNC patients, the patient's breathing was examined through swallowing apnea, but respiratory performance was not evaluated through intraoral pressure and respiratory function test. Swallowing dysfunctions are frequently seen in patients with head and neck cancer, both due to the pathophysiology of the disease and because the treatments applied due to the localization of the tumor affect the head and neck region, and the quality of life is low because these patients cannot reach rehabilitative approaches. In studies on the effects of chemotherapy and radiotherapy, which are included in the treatment of head and neck cancer patients, it has been proven in the literature that it causes a decrease in swallowing performance and neck endurance over time. Based on the literature and clinical experience, it can be concluded that there is currently no "gold standard" in the evaluation or treatment of dysphagia in patients with HNC. This result is also valid for the neck endura parameter in patients with head and neck cancer. However, in a study conducted with head and neck cancer patients, it was revealed that there is a correlation between subjective and objective evaluation scales. At the end of the study, it was aimed to evaluate the relationship between dysphagia, which is one of the treatment complications in patients, with respiratory performance, intraoral pressure and neck endura variables, and to look at the future study and rehabilitation methods from a different parameter.

Interventions

DIAGNOSTIC_TESTFiberoptic Endoscopic Evaluate Swallowing

Our choice in the study consists of subgroups that include Swallowing Assessment, Imaging Assessment and Neck Endurance measurements.

Sponsors

Istanbul Arel University
Lead SponsorOTHER
The Scientific and Technological Research Council of Turkey
CollaboratorOTHER
Saglik Bilimleri Universitesi
CollaboratorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosing head and neck cancer patients (larynx, nasopharynx, tongue, tonsil, parotid, retromolar trigone, lip, tongue root, hypopharyngeal cancers) * Statement with consent considering participating in the study * Disorders that cause obstacles due to the Function Test and intraoral passages

Exclusion criteria

* Presence of a chronic disease that prevents participation in the pulmonary function test and the study by the radiation oncology doctor and otolaryngologist. * Patients with swallowing problems due to previous illness or surgery * Acute surgical patient

Design outcomes

Primary

MeasureTime frameDescription
FEESthrough study completion, an average of 6 months.Fiberoptic Endoscopic Evaluate Parametres ( PAS, Yale Residue Scale, Murray Secretion Scale)
EAT-10 Scalethrough study completion, an average of 6 months.This scale includes 10 questions.
Neck arthrokinematics assessmentthrough study completion, an average of 6 months.Neck Endurance Test (30s), Neck ROM, Neck Disability İndex
Respiratory Function Testthrough study completion, an average of 6 months.FEV1, FEV1/FVC, FVC, PEF
İntraoral Mouth Pressurethrough study completion, an average of 6 months.MIP, MEP

Countries

Turkey (Türkiye)

Contacts

STUDY_DIRECTORRabia Kum Güler, PhD(c), PT

Istanbul Arel U

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026