Carpal Tunnel Syndrome (CTS)
Conditions
Keywords
carpal tunnel, ultrasound, power doppler
Brief summary
This prospective cohort study aims to evaluate median nerve cross-sectional area and intraneural vascularity using power Doppler ultrasonography in patients with carpal tunnel syndrome. Ultrasonographic findings will be compared between diabetic and non-diabetic patients. Clinical severity and electrophysiological findings will be correlated with ultrasonographic parameters.
Interventions
DIAGNOSTIC_TESTDoppler ultrasound
The predictive power of cross-sectional area and intraneural blood flow measured by ultrasound on surgical outcomes will be tested.
Sponsors
SB Istanbul Education and Research Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* clinically and electrophysiologically confirmed carpal tunnel syndrome * symptom duration \> 3 months * written informed consent
Exclusion criteria
* previous wrist surgery * cervical radiculopathy * inflammatory arthritis * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraneural Vascularity | Baseline | Intraneural blood flow will be evaluated using power Doppler ultrasonography at the level of the carpal tunnel inlet. The presence and degree of intraneural vascularity will be graded using a semi-quantitative scoring system: 0 = No detectable intraneural flow 1. = Single vessel signal 2. = Multiple vessel signals 3. = Marked hypervascularity The total score ranges from 0 to 3. Higher scores indicate increased intraneural vascularity. |
| Cross sectional Area | baseline | The cross-sectional area of the median nerve will be measured using ultrasonography at the level of the pisiform bone (carpal tunnel inlet) and proximal to transvers carpal ligament. Measurements will be obtained by tracing the inner border of the hyperechoic epineurium. Values will be recorded in square millimeters (mm²). Higher values indicate greater nerve swelling. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Boston Carpal Tunnel Questionnaire | Baseline, 3th and 6th months | Change in Symptom Severity Score of the Boston Carpal Tunnel Questionnaire The Boston Carpal Tunnel Questionnaire is a patient-reported outcome measure consisting of 11 questions assessing symptom severity. Each item is scored from 1 (no symptoms) to 5 (most severe symptoms). The total score ranges from 11 to 55. Higher scores indicate worse symptom severity. |
Outcome results
None listed