Hyperthermia
Conditions
Keywords
Hyperthermia, Exercise
Brief summary
This study will help us as scientists and clinicians understand how effective commonly used cooling protocols in emergency departments are and which of the protocols is the most effective. It consists of a single, approximately 1 hour preliminary session and five, approximately 3 hour experimental sessions, equaling an approximate 16 hour total time commitment. The purpose of this research is to test the effectiveness of three cooling protocols. 1. Cooling packs 2. "Ice Sheets", which are bed sheets soaked in ice water, wrapped around the participant, while a fan blows air on them. 3. Body bag filled with ice, commonly used in emergency departments to treat hyperthermia Additionally, a negative control (passive cooling in air-conditioned room) and a positive control (cold water immersion).
Interventions
PROCEDUREPassive cooling
During recovery, participants lie supine in an air-conditioned room
PROCEDURECooling packs
During recovery, participants lie supine while ice packs are applied to both sides of the neck, both arm pits, and both sides of the groin
PROCEDUREIce sheets
During recovery, participants are wrapped in bed sheets that have been soaked in ice water, while an electric fan blows air across their body
PROCEDUREBody bag cooling
During recovery, participants are placed in a body bag full of ice, and then have ice placed on top of their body, followed by zipping the body bag closed.
PROCEDURECold water immersion
During recovery, participants are submerged in a bath, up to their neck, in cold water water with ice
Sponsors
University of Colorado, Colorado Springs
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Active, healthy individuals
Exclusion criteria
* Pregnant or planning on becoming pregnant * Have a pacemaker * Currently taking any prescribed or over the counter medications or nutritional supplements known to influence thermoregulatory responses * Experience lingering pain from a previous musculoskeletal injury (i.e. knee, hip, or back pain) * Use tobacco/nicotine products
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rectal temperature cooling rate | The measurement occurs immediately upon completion of the exercise protocol. Time itself is part of the outcome variable and will vary between participants (~3 to 40 min post exercise protocol). | Following termination of the exercise protocol, at a core temperature above 39 degrees Celcius, participants will be cooled until they reach a core temperature of 38 degrees Celcius. The cooling rate in degrees Celcius per minute, is the primary outcome. |
Countries
United States
Contacts
CONTACTNathan Morris, PhD
Outcome results
None listed