French Registry: Late Gadolinium Enhancement in Hypertrophic Cardiomyopathy

Retrospective French Registry of Cardiovascular Magnetic Resonance Late Gadolinium Enhancement in Patients With Hypertrophic Cardiomyopathy

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07428031

Acronym

HCM-LGE

Enrollment

5000

Registered

2026-02-23

Start date

2026-03-01

Completion date

2036-03-01

Last updated

2026-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiomyopathy, Hypertrophic Cardiomyopathies

Keywords

Cardiac Magnetic Resonance, Cardiomyopathy

Brief summary

This study aims to create a registry of patients with hypertrophic cardiomyopathy, a condition characterized by excessive thickening of the heart muscle. This disease can sometimes lead to serious complications. Currently, the prognosis of these patients is mainly determined by clinical and echocardiographic parameters. Detection of myocardial fibrosis using cardiac MRI enables better risk stratification for these patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age ≥ 18 years 2. Ability to provide informed consent 3. HCM diagnosis referred for CMR assessment.

Exclusion criteria

1. Patients unable to provide informed consent, 2. Patients with a history of ischemic cardiomyopathy or myocarditis.

Design outcomes

Primary

Measure	Time frame	Description
To build a score using the "LGE granularity" concept for all-cause mortality prediction in HCM patients.	From Baseline to 5 years	All-cause mortality using the electronic French National Registry of Death (Institut National de la Statistique et des Etudes Economiques, INSEE registry).

Contacts

CONTACTThéo PEZEL, Dr

theo.pezel@aphp.fr+33 6 68 72 24 89

Outcome results