Children, Meatal Stenosis, Primary Nocturnal Enuresis
Conditions
Brief summary
This study aimed to investigate the association between meatal stenosis and primary nocturnal enuresis severity, and evaluated therapeutic outcomes following surgical correction.
Detailed description
Primary nocturnal enuresis (PNE) is a prevalent pediatric condition characterized by involuntary urination during sleep in children aged five years or older who have never achieved consistent nighttime dryness. The prevalence of PNE decreases with age, affecting approximately 15% of five-year-old and decreasing to 1-2% by adolescence. Meatal stenosis, defined as the pathological narrowing of the urethral meatus, is an underexplored potential factor. This condition is known to cause obstructed urinary flow, incomplete bladder emptying, and increased bladder pressure, all of which may contribute to enuresis. The incidence of meatal stenosis is higher in circumcised males but can also occur in uncircumcised males and females due to inflammation, trauma, or infection
Interventions
PROCEDUREMeatoplasty Primary nocturnal enuresis.
Patients diagnosed with primary nocturnal enuresis.
Sponsors
New Valley University
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
7 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* Male children aged 7-12 years. * Diagnosed with primary nocturnal enuresis. * Evaluated and treated at the study center between January 2021 and December 2024. * Confirmed diagnosis of meatal stenosis based on clinical examination and uroflowmetry when indicated. * Patients who underwent meatoplasty and completed the prescribed follow-up period.
Exclusion criteria
* Secondary enuresis (previously dry for ≥ 6 months before recurrence of bedwetting). * Known neurological disorders (e.g., spina bifida, cerebral palsy) or developmental delays. * Structural anomalies of the urinary tract other than meatal stenosis (e.g., posterior urethral valves, vesicoureteral reflux). * Children who did not complete the follow-up or had incomplete clinical records.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Association between Meatal Stenosis and primary nocturnal enuresis | 3 years from collecting the data from the database | Association between Meatal Stenosis and primary nocturnal enuresis was assessed to determine whether there is a significant relationship between the presence of meatal stenosis and the occurrence of primary nocturnal enuresis in male children aged 7-12 years. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Resolution of primary nocturnal enuresis post-meatoplasty | 3 years from collecting the data from the database | Resolution of primary nocturnal enuresis post-meatoplasty was assessed to assess the effectiveness of meatoplasty in resolving primary nocturnal enuresis in children with meatal stenosis. |
| Need for Revision Meatoplasty | 3 years from collecting the data from the database | Need for Revision Meatoplasty was assessed in patients due to persistent or recurrent meatal stenosis after the initial surgery. |
| Prevalence of Meatal Stenosis in primary nocturnal enuresis patients | 3 years from collecting the data from the database | Prevalence of Meatal Stenosis in primary nocturnal enuresis patients was assessed among children diagnosed with primary nocturnal enuresis within the study period (2021-2024). |
| Incidence of complications | 3 years from collecting the data from the database | Any complications or adverse events following meatoplasty, including infection, scarring, or urinary retention were recorded. |
Countries
Egypt
Outcome results
None listed