CT Scan, EUS Guided Biopsy, Pancreatic Lesions Located at the Body or the Tail
Conditions
Keywords
Triphasic Ct abdomen vs EUS-FNB, EUS-FNB
Brief summary
evaluate the relationship between triphasic CT and EUS findings and the characterization of pancreatic lesions.
Detailed description
Comparison Between Triphasic CT and EUS-FNB in characterization of Pancreatic Lesions
Interventions
DIAGNOSTIC_TESTFull clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings.
Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings.
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \*Adult patients (age\>18 years) presenting with focal pancreatic lesions detected on initial imaging. * Patients referred for further evaluation by triphasic CT and/or EUS-guided biopsy. * Patients able to provide informed consent
Exclusion criteria
* Previous pancreatic surgery. * Known metastatic disease at presentation. * Contraindications to contrast-enhanced CT (e.g. severe renal impairment, contrast allergy) * Contraindications to EUS or biopsy (e.g., coagulopathy uncorrected, severe cardiopulmonary instability). * Pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic accuracy of triphasic CT compared to EUS-guided biopsy in differentiating benign from malignant pancreatic lesions. | one year | the diagnostic accuracy of triphasic CT compared to EUS-guided biopsy in differentiating benign and malignant pancreatic lesions, calculated in terms of sensitivity, specificity, PPV, NPV, and overall accuracy, using final histopathological diagnosis as the reference standard. |
Contacts
CONTACTAhmed Abdullah Ashmawy, Prof. Dr
CONTACTMohamed Mahdy, ProfDr
Outcome results
None listed