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Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performance

Stimolazione Vibratoria Non-invasiva Per il Miglioramento Del Ritorno Sensoriale e Della Performance Motoria in Atleti Con Lesione al Legamento Crociato Anteriore

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07424066
Acronym
VIBMOT
Enrollment
35
Registered
2026-02-20
Start date
2025-05-20
Completion date
2026-12-31
Last updated
2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vibration

Keywords

vibratory stimulation, muscle spindle, muscle contraction, spinal reflex, somatosensory system

Brief summary

The goal of this interventional cross-sectional study is to evaluate motor responses to non-invasive vibratory stimulation applied to the hamstring muscle tendons in healthy individuals. Knee flexion and extension efforts, in both isometric and concentric contractions, will be tested. The investigators hypothesize that vibratory stimulation causes an increase in activity in the flexor muscles (hamstrings) and a decrease in the extensor muscles (quadriceps) of the knee in all motor tasks. It follows that during knee flexion (both concentric and isometric), vibratory stimulation should cause an increase in the distance between the angular trajectories of the knee obtained with and without vibratory stimulation (with a positive sign). The increased activity of the hamstring muscles would, in fact, contribute to increasing the velocity of the flexor movement. Conversely, during extensor movements (both concentric and isometric), vibratory stimulation should reduce the instantaneous velocity of the movement, therefore causing an increase in distance (with a negative sign) between the trajectories obtained with and without stimulation. Participants will be tested using an isokinetic dynamometer and they will be asked to perform the following motor tasks in a random order: concentric knee flexion, concentric knee extension, isometric knee flexion, and isometric knee extension. The dominant limb will be tested, only. The assessment will be performed one time.

Interventions

A vibratory stimulator will be applied to the back of the dominant leg, at the level of the hamstring muscle tendons. The stimulator consists of two small vibrating boxes fixed to the leg by means of an elastic band.

Sponsors

University of Milano Bicocca
Lead SponsorOTHER
Istituto Auxologico Italiano
CollaboratorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age equal to or greater than 18 years.

Exclusion criteria

* Neurological disorders. * Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements. * Cardiorespiratory disorders.

Design outcomes

Primary

MeasureTime frameDescription
Knee angleDay 1.Maximum distance (in degrees) between the knee trajectory obtained with and without vibratory stimulation.
Surface electromyography (sEMG)Day 1.Difference in sEMG between the muscle activity with and without vibratory stimulation, for each muscle (i.e., Quadriceps, Hamstrings, and Plantarflexor muscles).

Countries

Italy

Contacts

CONTACTStefano Scarano, Medical Doctor
s.scarano@auxologico.it+3902619116717
PRINCIPAL_INVESTIGATORCristiano Alessandro, Engineering

University of Milano Bicocca

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026