Sleep Disorder (Disorder)
Conditions
Keywords
sleep, high altitude, sleep disorder, cardiorespiratory parameters
Brief summary
Sleep organization and cardiorespiratory parameters are disrupted in extreme conditions such as high altitude. The pathophysiology of medical problems related to acute high-altitude exposure is partially understood, but sleep quality indicators are very rarely measured under these conditions. This lack of information is even more pronounced among employees subjected to cyclical exposure to high-altitude hypoxic stress, as is the case for the employees at the Pic du Midi. These 32 employees regularly report to their occupational physician difficulties in managing their sleep disorders, struggling to distinguish symptoms from objective changes in their sleep cycles. Among them, 13 are on call at the summit of the Pic du Midi (2,877 m), while 19 work there during the day and return home to a lower altitude at night to sleep. The investigators also wish to measure structural changes in sleep and its cardiorespiratory parameters using polysomnography in these 13 employees, comparing nights spent at home at normal altitude with those spent at the summit of the Pic du Midi. These changes will also be compared to those of a group of 19 employees who do not sleep at high altitude..
Interventions
OTHERSleep recording
Polysomnography and questionnaires.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Group "with on-call night at high altitude at the Pic du Midi": * Employed at the Pic du Midi for at least one month * Working nights at high altitude (at the Pic du Midi, altitude of 2877m) as part of their professional activity * Person affiliated with or covered by a social security scheme * Free, informed, and written consent signed by the participant and the investigator Night group "without on-call night at high altitude": * Employed at the Pic du Midi for at least one month * Not working nights at high altitude (at the Pic du Midi, altitude of 2877m) as part of their professional activity * Person affiliated with or covered by a social security scheme social * Free, informed and written consent signed by the participant and the investigator
Exclusion criteria
* For all participants: * History of cardiovascular disease * Use of cardiovascular/psychotropic medication * Participant under legal guardianship or other protective regime (guardianship, curatorship) * Pregnant or breastfeeding woman * French language proficiency insufficient to complete the questionnaires
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of sleep efficiency (total sleep time / total sleep period) under high altitude conditions (at 2877 m) versus without increased altitude (at home) | 1 week after the inclusion | Sleep efficiency will be compared, according to the ratio = total sleep time (TST)/ total sleep period (PTS) calculated from a polysomnographic recording, between the night spent at high altitude (2877m, at PIC du MIDI) and the second night spent at home (not increased altitude) among PIC du MIDI employees performing on-call nights at high altitude. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of sleep parameters in high altitude conditions versus without increased altitude for the group "with on-call night at high altitude at Pic du Midi" | 1 week after the inclusion | Sleep parameters (determined according to the criteria of the American Academy of Sleep Medicine (AASM)) measured from a polysomnographic recording will be compared in high altitude conditions versus without increased altitude. |
| Measurement of sleep parameters in low altitude conditions for the group "without on-call nights at high altitude" | 1 week after the inclusion | Sleep parameters (determined according to the criteria of the American Academy of Sleep Medicine (AASM)) will be measured from a polysomnographic recording under conditions without altitude gain. |
| Evaluation of the relationship between sleep quantification criteria and sleep disorder criteria | 1 week after the inclusion | Comparison of questionnaire responses and polysomnographic recording |
| Correlation between cardiac parameters and sleep efficiency. | 1 week after the inclusion | Correlation between heart rate variability and sleep efficiency using polysomnography recording |
| Comparison of sleep parameters, in conditions without increased altitude, between the 2 groups of participants | 1 week after the inclusion | Comparison of sleep parameters (determined according to the criteria of the American Academy of Sleep Medicine (AASM)) from the polysomnography recording between the two groups in conditions without increased altitude |
Countries
France
Contacts
CONTACTRachel DEBS, MD
Outcome results
None listed