Comparison Between Two Drugs in Sedation of Upper GI Endoscopy

Ketamine - Dexmedetomidine(Ketodex) Versus Propofol -Midazolam for Sedation in Patients Undergoing Upper Gastrointestinal Endoscopy

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07423676

Enrollment

Registered

2026-02-20

Start date

2026-03-01

Completion date

2026-05-02

Last updated

2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation During GI Endoscopy

Keywords

Sedation

Brief summary

The goal of this clinical trial is to compare time of sedation between two drugs administered to patients undergoing upper gastrointestinal endoscopy Primary outcome : Time of sedation : is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs Secondary outcome : * Recovery time :is the time to reach score 2 of modified Ramsay sedation score starting from injecting bolus dose of study drugs . * Hemodynamics (MAP,HR) & oxygen saturation * Drug side effects (nausea,vomitting,agitation) * Endoscopist satisfaction

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 60 Years

Inclusion criteria

* Patient acceptance * Adults aged 21-60 years. * Both sexes * BMI\<35 kg/m2 * ASA physical status :I\& II * Patients Undergoing Gastrointestinal endoscopy * Duration \<30mintues

Exclusion criteria

* • Known allergy to any of the study drugs * Unstable Cardiovascular disease * Moderate to severe respiratory diseases

Design outcomes

Primary

Measure	Time frame	Description
Comparison between time of sedation between ketamine Dexametomidine and propofol midazolam in sedation of GI endoscopy	Baseline	Time of sedation :is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs
Comparison time of sedation between ketamine Dexametomidine and propofol midazolam in sedation of GI endoscopy	Baseline	Time of sedation:is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs
Comparison of time of sedation between ketamine Dexametomidine g	Basline	• Time of sedation :is the time to reach score 5 of modified Ramsay sedation score starting from injecting bolus dose of study drugs .

Contacts

CONTACTAhmed Esam Hamad, Register

tahawy188@gmail.com+201095529439

PRINCIPAL_INVESTIGATORDoaa Mohamed Farid, MD

Doaa mohamed Farid

STUDY_DIRECTORRehab Abdalla Wahdan, MD

Rehab Abdalla Wahdan

PRINCIPAL_INVESTIGATOROlfat Monium Abraham, MD

Olfat abdelmonium Ebrahim

Outcome results