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Overlooked Barrier To Discontinuing Bont-A Therapy

Is The Insuffıcıent Patıent Informatıon An Overlooked Barrıer To Dıscontınuıng Bont-A Therapy For Post-Stroke Spastıcıty? A Retrospectıve Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07422428
Enrollment
81
Registered
2026-02-20
Start date
2024-09-23
Completion date
2025-04-05
Last updated
2026-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Stroke Spastic Hemiplegia

Keywords

Botulinum toxin, Spasticity, Stroke, Treatment Discontinuation

Brief summary

This study aims to evaluate patient adherence to botulinum toxin (BoNT-A) treatment and identify the factors contributing to its discontinuation. This retrospective cohort study analyzed the medical records of patients who received at least one botulinum toxin treatment for post-stroke spasticity (PSS) from 2012 to 2024. Eighty-one enrolled patients responded to structured questions about their reasons for not consistently continuing BoNT-A treatment.

Interventions

OTHERprovide information by phone

Previous studies did not question why patients thought they did not benefit from the injection. For example, the expectations of patients who said they did not benefit were excessive.

Sponsors

Suleyman Demirel University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* included chronic-phase ischemic or hemorrhagic stroke and spasticity in the upper and/or lower limbs.

Exclusion criteria

* Patients younger than 18 years, those who had passed away, and those who could not be reached by phone were excluded from the study.

Design outcomes

Primary

MeasureTime frameDescription
Primary Outcome2012-2024Most PSS patients received only one BoNT-A injection over 12 years

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026