Elderly, Epilepsy
Conditions
Brief summary
This prospective interventional study was conducted between 2023 and 2025 at the Department of Neurology of Bouali Sina Hospital. Consecutive elderly patients presenting with epilepsy were screened for eligibility. The diagnosis of epilepsy was confirmed by the treating neurologist. The patients underwent treatment with levetiracetam. Primary and secondary outcomes were investigated as was explained before.
Interventions
Treatment with levetiracetam tablets
Sponsors
Nasim Tabrizi
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥60 years 2. Diagnosis of epilepsy
Exclusion criteria
1. Chronic kidney disease requiring dialysis 2. History of psychotic disorders or current use of anxiolytic, antidepressant, or antipsychotic medications 3. Current use of antiseizure medications for any reason
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Seizure free rate | 12 months | The rate of patients who stayed seizure-free after drug initiation |
| Retention rate | 12 months | The rate of patients who continue taking drug |
| Time to first seizure | at occurrence of first seizure | The interval between starting drug and recurrence of seizure |
| Time to withdrawal | the day that the patient stops taking drug | The interval between starting drug and stoping its use |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Tolerability rate | 12 months | the rate of patients that forfeit participation in the study due to adverse effects |
Countries
Iran
Outcome results
None listed