Mechanical Ventilator Care
Conditions
Keywords
humidification, Passive humidification
Brief summary
Adequate humidification is essential for intubated patients because dry medical gases can cause thick secretions and dangerous endotracheal tube blockages. A clear correlation exists between exhaled and inhaled humidity delivered by heat and moisture exchanger. The objective of this study is to measure the temperature of exhaled gases in intubated patients in order to accurately calculate the absolute humidity during the expiratory phase. These data will allow for a more accurate reproduction of real clinical conditions during bench testing and will improve the assessment of heat and moisture exchanger performance device evaluation.
Detailed description
Previous clinical studies suggest that real expiratory humidity in intubated patients is close to 35 mg H₂O/L, with expiratory temperatures around 32-33 °C or slightly lower. However, data are limited, heterogeneous, and often derived from anesthetized patients. Therefore, accurate measurement of expiratory temperature in intensive care patients under normothermia and across varying body temperatures is necessary to define realistic simulation standards and ensure reliable heat and moisture exchanger performance evaluation on a bench. A relationship between expiratory gases temperature and expiratory humidity exist.
Interventions
OTHERExpiratory gases temperature
Measure expiratory gas temperature immediately before the passive humidifier in intubated ICU patients and evaluate the relationship between body temperature and expiratory temperature.
Sponsors
Laval University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (≥18 years) * Intubated and mechanically ventilated in the intensive care unite * Using passive humidification (Heat and Moisture exchanger)
Exclusion criteria
* PEEP set \< 12 cmH₂O * Inhaled nitric oxide therapy * Tracheostomy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Expiratory gas temperature | H0, up to 60 minutes after inclusion | Measure expiratory gas temperature immediately before the passive humidifier |
| Relationship between body temperature and expiratory temperature. | H0, up to 60 minutes after inclusion | Evaluate the relationship between body temperature and expiratory temperature |
Secondary
| Measure | Time frame |
|---|---|
| Estimate expiratory absolute humidity based on measured temperature | H0, up to 60 minutes after inclusion |
Countries
Canada
Contacts
CONTACTFrancois Lellouche, MD, PhD
Outcome results
None listed