Mild Cognitive Impairment (MCI)
Conditions
Keywords
mild cognitive impairment, acceptance and commitment therapy, neuropsychiatric symptoms
Brief summary
This study aims to develop an automated instant message-delivered intervention (i.e., EMI) for people with mild cognitive impairment to reduce their NPS, and to investigate the feasibility and effectiveness of the intervention.
Detailed description
1. Message contents: The message content library will consist of four parts: 1.orientation, 2. brief mild cognitive impairment education messages, 3. acceptance and commitment therapy messages, 4.booster message. 2. Message delivery * Regular messages: The messages in the four parts will be sent regularly to each participant. As personalisation is a core process subject to behavioural changes, the timing of the messages will be determined based on participants' preferences. To save labour and increase efficiency, the investigators will develop a message 'scheduler' program. The investigators will pre-set the message scheduler, which will then automatically send out content to the participants according to their preferences. The development of the program is highly useful particularly in cases which participants prefer to receive messages during non-office hours. * Real-time support messages (chat-type): Chat-based support will be given to the participants as an extension of the regular messages. However, the participants will be informed beforehand that the RA will only play a supportive role and will not provide formal care. The number of the chat messages will not be limited, but the real-time support messages will only be provided during working hours on weekdays to limit the RA's workload. Control Group: The control group will receive instant messages about mental health management from GovHK website (https://www.gov.hk/en/residents/health/mental/), which is open to the public.
Interventions
Participants in intervention group will receive the EMI for 9 weeks. Based on the steps of mobile message development recommended by Abroms, et al., we will develop a message content library and protocol for EMI delivery.
BEHAVIORALgeneral mental health management
Participants in control group will receive the messages for 9 weeks. The control group will receive instant messages about general mental health management from the HKSAR Government website, which is open to the public (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), with reminder text messages of follow-up surveys.
Sponsors
The University of Hong Kong
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Community-dwelling adults aged ≥ 50 years * HK-MoCA score ranged from 18 to 22 * MBI-C ≥7 * SCD-9 ≥3 * IADL =18 * Able to read and communicate in Chinese * Able to use the text or voice messaging function on a smartphone
Exclusion criteria
* Clinical diagnosis of dementia * Clinical diagnosis of psychiatric disease * Currently participating in any type of psychological or behavioural intervention for NPSs * Currently taking psychiatric medication * Currently receiving acute care or post-acute hospitalization care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MBI-C scores | at baseline, 10th week and 24th week | The primary outcome will be MBI-C scores to assess NPSs. A higher MBI-C scores will indicate a higher level of neuropsychiatric symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Depressive symptoms (PHQ-9) | at baseline, 10th week and 24th week | Each item was scored on a 4-point scale (0 "not at all" to 3 "nearly every day"). The total score is calculated by summing up the score of all items (range 0-27). High scores indicate worse depressive symptoms. |
| Anxiety symptoms (GAD-7) | at baseline, 10th week and 24th week | A 7-item scale with score ranging from 0 to 21, higher scores indicate higher severity of anxiety symptom |
| Quality of life (EuroQol 5-dimension 5-level questionnaire [EQ-5D-5L]) | at baseline, 10th week and 24th week | The EQ-5D-5L assesses five health dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, each rated on five levels of severity, with scores ranging from -0.864 to 1, where higher scores indicate better quality of life. Additionally, it includes a visual analogue scale (VAS), ranging from 0 (the worst health imaginable) to 100 (the best health imaginable). |
| Cognitive functions (HK-MoCA) | at baseline, 10th week and 24th week | The total score is calculated by summing up the score of all items. Higher scores indicate better cognitive function. |
| Acceptance of negative emotions and valued-based actions (AAQ-II) | at baseline, 10th week and 24th week | AAQ-II is a measure of psychological flexibility. Each item is rated on a 7-point scale from 1 = never true to 7 = always true. Scores range from 1-49. A lower score indicates a lower level of psychological flexibility. |
| Subjective Cognitive Decline scale (SCD-9) | at baseline, 10th week and 24th week | SCD-9 is a scale detecting subjective cognitive function. Higher socre indicate worse subjective cognitive function. |
Countries
Hong Kong
Contacts
CONTACTDoris Sau Fung Yu, Professor
PRINCIPAL_INVESTIGATORDoris Sau Fung Yu, Professor
School of nursing, The University of Hong Kong
Outcome results
None listed