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Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma

An Investigation of Tumor Genomics, Individual Risk Factors, and External Drivers of Health to Improve Health Outcomes for Patients With Meningioma

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07418775
Enrollment
3000
Registered
2026-02-18
Start date
2026-04-30
Completion date
2032-01-01
Last updated
2026-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningioma of Brain, Meningioma, Brain Tumor

Brief summary

Meningiomas are the most common primary brain tumor, and some groups are diagnosed with higher-grade tumors and have clinically worse outcomes. This study investigates social determinants of health and individual risk factors that may be associated with meningioma.

Detailed description

PRIMARY OBJECTIVES: I. To assess prevalence and distribution of social and structural determinants of health (SSDH) among meningioma patients. II. To assess disparities in SSDH among meningioma patients of different races. OUTLINE: This is an observational study. Participants will complete a survey and have their medical records reviewed.

Interventions

BEHAVIORALQuestionnaire

A questionnaire will be administered in person or online

Medical records will be reviewed for study specific data collection

Sponsors

University of California, San Francisco
Lead SponsorOTHER
National Cancer Institute (NCI)
CollaboratorNIH

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Adults ≥18 years of age * Able to speak and read English * Diagnosed with a meningioma

Exclusion criteria

* Active psychiatric issues (suicidality, active psychosis, grave disability, etc.) * Inability to consent secondary to severe neurologic deficit or psychiatric distress * Inability to complete survey secondary to severe neurologic deficit or psychiatric distress

Design outcomes

Primary

MeasureTime frameDescription
Identifying potential social and structural determinants of health (SSDH)Up to 5 yearsThe prevalence of SSDH factors such as race and ethnicity, birthplace, relationship status, sexual orientation/gender identity, education level, socio-economic status, access to care, reproductive/menstrual history, health factors and medication use, chemical and radiation exposure, smoking history, and perceived stress for participants with meningioma will be analyzed using multilevel logistic and linear models accounting for geographical clustering.
Distribution of social and structural determinants of healthUp to 5 yearsThe distribution of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.
Identify disparities in social and structural determinants of health (SSDH)Up to 5 yearsDisparities of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

Countries

United States

Contacts

CONTACTZora Arum
zora.arum2@ucsf.edu877-827-3222
PRINCIPAL_INVESTIGATORDavid Raleigh, MD, PhD

University of California, San Francisco, San Francisco, California 94143

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026