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Corneal Endothelial Cell Changes In Silicon Filled Eye

Corneal Endothelial Cell Changes In Silicon Filled Eye

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07418606
Acronym
Endothelium
Enrollment
40
Registered
2026-02-18
Start date
2025-06-15
Completion date
2026-09-20
Last updated
2026-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhegmatogenous Macula-off Retinal Detachment

Keywords

Endothelial cells, Silicone oil

Brief summary

The aim of this study is to evaluate corneal endothelial cell changes after pars plana vitrectomy in Rhegmatogenous Retinal detachment , compare the results using different silicon oil viscositites , and assess whether these changes are reversible after silicone removal or not .

Detailed description

The aim of this study is to evaluate corneal endothelial cell changes after pars plana vitrectomy in Rhegmatogenous Retinal detachment , compare the results using different silicon oil viscositites , and assess whether these changes are reversible after silicone removal or not .

Interventions

None listed

Sponsors

Minia University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

\- All patients with Rhegmatodenous retinal detachment which need PPV will be included in this study.

Exclusion criteria

* Patients with corneal dystrophies or degeneration. * Patients with a history of refractive surgery, either corneal or phakic lOL implantation. * Patients with a history of keratoplasty. * Patients with history of retinal detachment surgery in the same eye. * Recurrent cases during the follow-up period will be removed from the study. 6. patients with gas tamponade 7. patients with silicon oil 1000 cs 8. patients with Retinal pathologies such as macular hole , diabetic changes 9. patients undergo phacovitrectomy

Design outcomes

Primary

MeasureTime frameDescription
Corneal Endothelial Cell Changes In Silicon Filled Eye .4 monthsCorneal Endothelial Cell Changes cell density ( cells/ mm) , coeffient variation(%) In Silicon Filled Eye at 1 and 3 months postoperative

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 1, 2026