Infertile Women With Pelvic Adhesions
Conditions
Brief summary
Infertility is agrowing concern affecting million of couples worldwide,with infertility being asignificant subset, infertility is define as inability to achieve pregnancy after one year of regular unprotected sexual intercours Among these , pelvic Adhesions present amajor challenge in reproductive medicine as they can lead to tubal occulsion and uterine cavity distortion Saline infusion sonohysterography (SIS)has emerged as minimally invasive,cost effected,and well tolerated alternative for assessing uterine and tubal abnormalities in infertile patient SIS involve the introduction of sterile saline into the uterine cavity under ultrasound guidance ,enhancing the visualization of Endometrial lining, intrauterine abnormalities and tubal patency,compared to HSG, SIS offer several advantages including the avoidance of radiation exposure, better patient comfort and the ability to stimultaneously assess the myometrium and adenxal structure
Interventions
DIAGNOSTIC_TESTSaline infusion sonohysterography in Detection of pelvic Adhesions in infertile women
Introduction of sterile saline into uterine cavity under ultrasound guidance to detect endometial lining and tubal patency
Sponsors
Sohag University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* infertile women aged 18-45yr Patient suspected to have pelvic Adhesions Women with normal ovulatory function and normal husband semen analysis
Exclusion criteria
* active pelvic infection or abnormal vaginal bleeding Pt with cervical stenosis Congenital uterine mullerian anomalies Pt with pelvic malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic Accuracy of saline infusion sonohysterography (SIS): sensitivity,specificity, positive predictive value(PPV) and negative predictive value (NPV) for detecting pelvic Adhesions compared to Laparoscopy in infertile women | One year | dorsolithotomy position and Speculum insertion into vagina and catheter insetion into uterine cavity inflated with 1\_2ml of saline to secure placement with infusion of 10\_20 ml of sterile saline into uterine cavity through the catheter while performing transvaginal ultrasound imaging |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Uterune and tubal findings: presence of tubal blockage, hydrosalpinx or peritoneal adhesions | One year | Infusion of saline intrauterine undertransvaginal ultrasound imaging for detection of tubal block or peritoneal adhesions in infertile women |
Countries
Egypt
Outcome results
None listed