Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor

Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor at Term Pregnancy

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07416487

Enrollment

Registered

2026-02-18

Start date

2025-02-01

Completion date

2025-12-31

Last updated

2026-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor

Brief summary

There are gaps in the local data regarding the comparative effectiveness of Foley catheter versus misoprostol for induction of labor (IOL). Therefore, the current study was planned with the objective of comparing the mean induction-to-delivery interval of Foley catheter versus misoprostol for IOL in singleton term pregnancy.

Detailed description

Although systematic reviews and meta-analyses have compared the effectiveness and safety of pharmacologic, nonpharmacologic, mechanical, and combined methods of cervical ripening and labor induction, the optimal method of IOL is still debatable. The findings would be helpful in further assessing the conflicting evidence and furnishing the limited data regarding the use of Foley catheters or misoprostol in patients undergoing IOL from local setups.

Interventions

DRUGMisoprostol

Women received intravaginal misoprostol 25 μg 4 hours apart, up to a maximum of four doses.

DEVICEFoley catheter

An intracervical Foley catheter (16 F) was inserted into the patients. The balloon was inflated with 30 mL of sterile normal saline solution and was kept in place until it expelled spontaneously.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Pregnant females * 18-40 years * With a singleton term pregnancy (37-41) weeks * Parity \< 4 * Vertex presentation (on ultrasound scan) * Intact membranes (on history and clinical examination) * Going through labor induction

Exclusion criteria

* With a previous uterine surgery * Non-reassuring cardiotocography (CTG) * Oligohydramnios (on ultrasound scan) * Intrauterine growth restriction (IUGR) (on ultrasound scan) * Abruptio placenta (on ultrasound scan).

Design outcomes

Primary

Measure	Time frame	Description
Delivery of the fetus	24 hours	Induction-to-delivery interval was calculated from the insertion of the Foley catheter or misoprostol until the delivery of the fetus in hours.

Countries

Pakistan

Contacts

PRINCIPAL_INVESTIGATORZunera Sumbal

D.G. Khan Medical College/Allama Iqbal Teaching Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026