Hypotension After Spinal Anesthesia
Conditions
Brief summary
To assess the hemodynamic difference after spinal anesthesia with hyperbaric bupivacaine and isobaric bupivacaine in elective cesarean section
Interventions
DRUGSpinal anesthesia with hyperbaric bupivacaine
Spinal anesthesia with hyperbaric bupivacaine according to height
DRUGSpinal anesthesia with isobaric bupivacaine
Spinal anesthesia with Isobaric bupivacaine according to height
Sponsors
Liaquat National Hospital & Medical College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ASA II parturient with normal pregnancy Parturients undergoing elective cesarean section under spinal anesthesia Parturient refusing normal trial of labor, planned for ELLSCS under spinal anesthesia
Exclusion criteria
* Patient refusal Parturient with known drug allergy to local anesthetics Parturients undergoing emergency cesarean section Spinal anesthesia converted to general anesthesia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maternal hypotension | Baseline | Incidence of maternal hypotension (MAP \< 60 mm Hg or drop in MAP \> 20% of the baseline) within 5 minutes after intrathecal drug administration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maternal heart rate trend | Baseline | Maternal heart rate as bpm |
| Use of vasopressors | Baseline | Requirement for vasopressors |
| Nausea and vomiting | Baseline | incidence of nausea/vomiting due to hypotension |
| APGAR score | Baseline | Fetal Apgar scores at 1 and 5 minutes |
| Conversion to general anesthesia | Baseline | Patients requiring general anesthesia after spinal anesthesia |
| Maternal MAP trend | Baseline | MAP as mm Hg |
Countries
Pakistan
Contacts
CONTACTAnum Fatima, MBBS
Outcome results
None listed