Male Sexual Function
Conditions
Keywords
Anti-reflux Ureteral Stents, Standard Double J Tubes, ED, LUTS, IIEF
Brief summary
Objective: To compare the effectiveness of anti-reflux ureteral stents on improving erectile function and quality of life of patients with ureteral stents. Methods and Populations: A total of 100 male patients who required ureteral stent placement after ureteroscopic lithotripsy were randomly assigned to two groups: those in Group T (n=50) received a standard double-J-stent, while those in Group A (n=50) underwent implantation with anti-reflux ureteral stent. Follow up for 8 weeks after surgery, including reproductive hormones and inflammation marks, Beck's depression scale, IIEF and statistics on the frequency of symptoms such as hematuria.
Interventions
PROCEDURERoutine laser lithotripsy
Routine laser lithotripsy was done for the ureteral calculi, and a 6 Fr polyurethane DJ stent (Inlay Optima®, Bard Medical, Covington, GA) or INNOVEX, according to the groups, was inserted under fluoroscopic and cystoscopic guidance. Appropriate length was adjusted according to patient's height. Routine X-ray of the kidneys, ureter and bladder (KUB) was taken for all patients before home discharge to confirm the proper stent positioning. All patients are advised to avoid alcohol, until 4 weeks after surgery when the ureteral stent is removed in our institution. General information such as preoperative age, body mass index, diameter of ureteral calculi, and degree of hydronephrosis, operation time were obtained. Follow up for 8 weeks after surgery, including reproductive hormones and inflammation marks, Beck's depression scale, IIEF and statistics on the frequency of symptoms such as hematuria.
Sponsors
Rong Wang
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* male sexually active patients with unilateral ureteral calculi who underwent ureteroscopy with laser lithotripsy and needed post-procedure stent
Exclusion criteria
* Patients were excluded if they included the following criteria: (1) age under 18 or over 50 years, (2) history of previous ureteral stenting, (3) bilateral stents, (4) moderate or severe ureteral stricture need long-term stenting (on regular exchange), (5) bladder pathology and overactive bladder, (6) symptomatic benign prostatic hyperplasia, (7) moderate or severe urinary tract infection, (8) moderate or severe cardiovascular disease, hepatic dysfunction and diabetes, (9) previous use of selective alpha-1-blocker and/or antimuscarinic agent, (10) pre-op IIEF-5 ≤ 21.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in IIEF score | Patients were followed up postoperatively according to a bi-weekly schedule, with clinical assessments at 2, 4, 6, and 8 weeks |
Countries
China
Outcome results
None listed