Healthy Subjects
Conditions
Brief summary
The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.
Interventions
MRI examination of the head and neck, and torso for the measurement of electrical properties
Sponsors
Central Hospital, Nancy, France
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Person aged between 6 and 12, 20 and 40 years or aged 70 years and above * Person affiliated with a social security scheme or beneficiary of such a scheme * Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form
Exclusion criteria
* Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device * Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters * Pregnant woman, woman in labor, or breastfeeding mother * Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Conductivity in S/m at the head level in subjects aged 6 to 12 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years |
| Conductivity in S/m at the head level in subjects aged 20 to 40 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years |
| Conductivity in S/m at the head level in subjects aged 70 and above | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above |
| Conductivity in S/m at the neck level in subjects aged 6 to 12 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years |
| Conductivity in S/m at the neck level in subjects aged 20 to 40 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 20 to 40 years |
| Conductivity in S/m at the neck level in subjects aged 70 and above | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 70 and above |
| Conductivity in S/m at the torso level in subjects aged 6 to 12 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 6 to 12 years |
| Conductivity in S/m at the torso level in subjects aged 20 to 40 years | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 20 to 40 years |
| Conductivity in S/m at the torso level in subjects aged 70 and above | Baseline (J0) | Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 70 and above |
Countries
France
Contacts
CONTACTMarc BRAUN, MD, PhD
CONTACTGuillaume DROUOT, PhD
Outcome results
None listed