Pancreatic Tumor Patients Who Consecutively Underwent Minimally Invasive or Open Pancreatic Surgery With Venous Reconstruction
Conditions
Brief summary
The prognostic differences between open and minimally invasive radical pancreatic surgery combined with venous resection and reconstruction remain controversial, and there is a lack of high-quality evidence-based medical evidence to support either approach. Therefore, this study intends to conduct a retrospective cohort analysis, planning to enroll pancreatic cancer patients who have undergone radical pancreatic surgery (open vs. minimally invasive) combined with venous resection and reconstruction from multiple hospitals both domestically and internationally, and to collect relevant data. The primary objective is to evaluate the differences in postoperative thrombosis and the incidence of severe complications between the two groups. Furthermore, prognostic data will be collected to assess the impact of open versus minimally invasive pancreatic surgery combined with venous resection and reconstruction on both short-term and long-term all-cause mortality in pancreatic cancer patients.
Interventions
None listed
Sponsors
First Affiliated Hospital Xi'an Jiaotong University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosis of malignant pancreatic or periampullary lesions requiring surgical pancreatic resection; preoperative imaging confirming venous involvement; undergoing pancreatic resection with simultaneous venous resection and reconstruction; and availability of complete postoperative outcome data, including thrombosis and complication grading.
Exclusion criteria
* preoperative confirmation of distant metastasis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidences of major complication | within 30 postoperative days | Postoperative complications were defined and graded according to the Clavien-Dindo (C-D) classification system ranging from Grade I (minor deviation) to Grade V (death), with C-D ≥III being considerated as major complication |
| incidences of postoperative thrombosis | within 30 postoperative days | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative recurrence-free survival | before discharge, and at 3, 6, 12, 18, 24, 30, and 36 months postoperatively |
| incidence of postoperative post-pancreatectomy hemorrhage | within 30 postoperative days |
| incidence of postoperative pancreatic fistula | within 30 postoperative days |
| incidence of postoperative delayed gastric emptying | within 30 postoperative days |
| postoperative overall survival | before discharge, and at 3, 6, 12, 18, 24, 30, and 36 months postoperatively |
Countries
China
Outcome results
None listed