Efficacy and Safety of VasoClip® vs. WeckClip® for Robotic Urologic Surgery

The Clinical Trial to Evaluate the Efficacy and Safety of an Implantable Vascular Clip (Vaso Clip).

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07413120

Enrollment

Registered

2026-02-17

Start date

2020-05-07

Completion date

2020-12-31

Last updated

2026-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Cancers, Prostate Cancer (Adenocarcinoma), Urothelial Cancer

Keywords

clip, randomized controlled trial, robotics, surgical clip

Brief summary

This prospective, randomized, Phase III trial evaluates the efficacy and safety of VasoClip®, a novel polymer surgical clip with a Z-groove and an elastic notch, designed to enhance mechanical grip and prevent slippage. Forty patients undergoing robotic urologic surgery were randomized to receive either VasoClip® or the standard WeckClip®. The primary objective is to compare ligation success rates, assessed through a double-blinded review of surgical videos. This study aims to provide clinical evidence for the performance and safety of this structurally improved device in robot-assisted procedures.

Interventions

DEVICEVasoClip®

A novel polymer ligating clip featuring a proprietary Z-groove and elastic notch architecture. Designed to maximize the friction coefficient and interlocking with soft tissue during robotic urologic surgery. The clips are applied for vessel and tissue ligation during procedures such as radical prostatectomy or nephrectomy.

DEVICEWeckClip®

Conventional standard polymer ligating clip (Hem-o-lok system) used as an active comparator. Used for the same indications and surgical procedures as the experimental group to evaluate the comparative efficacy and safety.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 20 years or older. * Scheduled for robotic or laparoscopic urologic surgery where the use of polymer ligating clips is anticipated. * Voluntary informed consent.

Exclusion criteria

* Clinically significant coagulation disorders (PT-INR \> 1.2). * Severe vascular diseases (e.g., peripheral arterial occlusion, microvascular heart disease). * Comorbidities inducing excessive bleeding (e.g., active urinary tract infection, liver cirrhosis). * Conditions affecting blood cell or platelet production (e.g., leukemia). * Known coagulation factor deficiencies (e.g., hemophilia)

Design outcomes

Primary

Measure	Time frame	Description
Ligation success rate	Intraoperative	The rate at which clips are ligated as intended and maintained through the end of the procedure.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026