Asthma Acute, Asthma Childhood, Asthma Crisis, Asthma in Children
Conditions
Keywords
asthma attack, exacerbation,
Brief summary
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
Detailed description
Patients aged 6 to 17 years presenting to the emergency department with an acute asthma exacerbation were included. Clinical outcomes were compared between a pre-intervention period (October 2024-May 2025) and a post-intervention period (October 2025-May 2026). Between the two study periods, a structured educational intervention targeting medical and nursing staff was implemented. The intervention consisted of didactic lectures, clinical simulation sessions, case-based discussions, and the dissemination of updated diagnostic and therapeutic flowcharts based on the 2025 Global Initiative for Asthma (GINA) guidelines.
Interventions
None listed
Sponsors
Meyer Children's Hospital IRCCS
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Age between 6 and 17 years * Presentation to the emergency department with a diagnosis of acute asthma exacerbation * Evaluation in the emergency department of one of the participating centers during the study periods
Exclusion criteria
* Age \< 6 years or \> 17 years * Diagnosis other than acute asthma exacerbation * Incomplete or missing clinical data * Patients transferred from other hospitals already treated for the same episode * history of allergy to any drugs used in the protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the number of correctly reported diagnoses before and after intervention | Pre-intervention and through study completion, an average of 9 months | Assessment of adherence to guideline-based diagnostic and therapeutic management of pediatric patients presenting with acute asthma exacerbations in the emergency department. |
| Percentage of patients with correct timing, dosage, and method of drug administration before and after intervention | Pre-intervention and through study completion, an average of 9 months | — |
| Percentage of patients with correct follow-up at discharge | Pre-intervention and through study completion, an average of 9 months | — |
| Percentage of patients in whom additional drugs are used in refractory cases | Pre-intervention and through study completion, an average of 9 months | — |
| Percentage of patients with correct therapy at discharge | Pre-intervention and through study completion, an average of 9 months | — |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of acute asthma exacerbations | Pre-intervention and through study completion, an average of 9 months | Number of emergency department visits for acute asthma exacerbations among pediatric patients during the pre- and post-intervention periods. |
Countries
Italy
Contacts
CONTACTGrazia Fenu
Outcome results
None listed