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Degenerative Spondylolisthesis Accompanying LSS: Do We Need Fusion?

Degenerative Spondylolisthesis Accompanying LSS: Do We Need Fusion?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07410871
Enrollment
52
Registered
2026-02-13
Start date
2025-01-01
Completion date
2025-06-29
Last updated
2026-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative Spondylolisthesis, Fusion, Lumbar Spinal Stenosis

Brief summary

This study aimed to compare clinical results of decompression alone using minimal invasive unilateral laminotomy for bilateral decompression versus classical decompression and instrumentation and fusion.

Detailed description

The term "lumbar spinal stenosis" (LSS) describes the anatomical narrowing of the spinal canal, which occurs in older people because of spinal ageing. Initial treatment is usually medical. Surgical management is recommended for patients with failed non-surgical trials. As claudication is always the main complain, lumbar canal decompression is the traditional surgical treatment. Although adding instrumentation and fusion is not uncommon and widely used. In the literature, the benefit of fusion, is treating instability that causes degenerative spondylolisthesis, improve back pain if present, and avoid slippage progression, which possibly will occur with generous decompression and disruption of the posterior column.

Interventions

PROCEDUREUnilateral laminotomy decompression

Patients underwent unilateral laminotomy decompression.

PROCEDUREDecompression and fusion

Patients underwent a posterior decompression, (either with or without preservation of midline bands) was followed by instrumentation using pedicle screws with rods and intervertebral fusion device.

Sponsors

Kafrelsheikh University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age \> 50 years. * Both sexes. * Patients with symptoms of lumbar spinal stenosis (LSS) (neurogenic claudication) confirmed by magnetic resonance imaging (MRI), and a degenerative spondylolisthesis measuring at least 3 mm at the stenotic level on a plain X-ray.

Exclusion criteria

* Patients with excessive foraminal stenosis (a deformed nerve root in the intervertebral foramen). * Thoracolumbar scoliosis of greater than 20 degrees. * Patients with significant instability in plan radiography dynamic study. * Patients who had previous spine surgery at lumbar region.

Design outcomes

Primary

MeasureTime frameDescription
Assessment of low back pain14 months after the procedureLow back pain was assessed using the Oswestry Disability Index (ODI), 10-question self-report questionnaire to measure functional disability and quality of life. It yields a percentage score from 0% (no disability) to 100% (severe disability).

Secondary

MeasureTime frameDescription
Degree of pain14 months after the procedureEach patient was instructed about leg pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable").
Incidence of complications14 months after the procedureIncidence of complications were recorded.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026