Lateral Epicondylitis
Conditions
Brief summary
This retrospective, controlled clinical study aims to evaluate the effectiveness of a targeted biological support injection containing a hyaluronic acid and amino acid combination in patients with chronic lateral epicondylitis (tennis elbow). Medical records will be reviewed to compare outcomes between patients treated in routine clinical practice with a 3-dose injection regimen (weeks 0, 2, and 4) plus a home exercise program and those treated with a home exercise program alone. Key outcome measures include pain intensity (VAS), functional status (PRTEE), grip strength, and pressure pain threshold.
Interventions
DRUGHyaluronic Acid + Amino Acid Injection
3-dose injection protocol administered at weeks 0, 2, and 4.
BEHAVIORALHome Exercise Program
Standardized home exercise program for chronic lateral epicondylitis.
Sponsors
Sivas State Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged between 18 and 70 years. * Patients diagnosed with Lateral Epicondylitis (LE). * Presence of symptoms persisting for 6 weeks or longer. * Patients who were treated with either a 3-dose protocol of Hyaluronic Acid + Amino Acid injection combined with a home exercise program, or a home exercise program alone.
Exclusion criteria
* History of rheumatic disease. * History of malignancy. * Presence of radiculopathy or neuropathy. * Presence of peripheral circulatory disorders. * Congenital or acquired upper extremity deformities. * History of coagulopathy or current use of warfarin therapy. * Presence of prosthesis, metal implant, or internal fixator in the elbow region.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Pain Intensity (VAS) | Baseline, Week 4, and Month 3 | Pain intensity will be measured using a 10-cm Visual Analog Scale (VAS). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Functional Status (PRTEE Score) | Baseline, Week 4, and Month 3 | Functional disability and pain will be assessed using the Patient-Rated Tennis Elbow Evaluation (PRTEE). |
| Change in Grip Strength (Hand Dynamometer) | Baseline, Week 4, and Month 3 | Grip strength will be measured using a hand-held dynamometer. Measurements will be recorded in kilograms (kg). Higher values indicate greater strength. |
| Change in Pressure Pain Threshold (Algometry) | Baseline, Week 4, and Month 3 | Pressure pain threshold over the common extensor tendon will be measured using a handheld algometer. |
Countries
Turkey (Türkiye)
Outcome results
None listed