Small Bowel Diseases
Conditions
Brief summary
The aim of our study was to compare the utility and safety of SBE and DBE in pediatric patients.
Detailed description
The benefit of balloon-assisted enteroscopy (BAE) had been recently documented in pediatric patients, but no study has compared the use of single-balloon enteroscopy (SBE) and double-balloon enteroscopy (DBE) in pediatric patients to date. The aim of our study was to compare the utility and safety of SBE and DBE in pediatric patients. This retrospective study enrolled patients younger than 18 years between January 2015 and May 2024. Inverse probability of treatment-weighted (IPTW) adjustment was used to address the imbalance in variables. The outcomes included diagnostic yield, positive rate, complete enteroscopy, therapeutic yield, procedure times and complications.
Interventions
DEVICEsingle-bollon enteroscopy
one group use single-balloon enteroscopy (SBE) in pediatric patients
DEVICEdouble-bollon enteroscopy
one group use double-bollon enteroscopy
Sponsors
Shandong University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* This study retrospectively collected clinical data and endoscopic information of pediatric patients (≤18 years) with suspected small bowel disease who underwent BAE consecutively at a tertiary medical center (Qilu Hospital of Shandong University, Jinan, China) from January 2015 to May 2024.
Exclusion criteria
(1) refusal for consent; (2) contraindication for deep sedation; (3) patients with incomplete clinical data and endoscopic information; (4) oral enteroscopy cannot pass the pylorus, and anal enteroscopy cannot pass the ileocecal valve. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| diagnostic yield | From Baseline to the finish of enteroscopy | Diagnostic yield was defined as the percentage of procedures with a disease-specific definitive endoscopic diagnosis. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Positive rate | from baseline to the finish of enterscopy | Positive rate as the proportion of patients with positive findings among all patients receiving BAE. |
| Complete enteroscopy | start to the finish of the enteroscopy | Complete enteroscopy was defined as intubation of the entire small bowel by unidirectional (antegrade or retrograde route) or bidirectional enteroscopy. |
| Therapeutic yield | frome baselin to finish of the enteroscopy | Therapeutic yield was defined as the proportion of enteroscopies in which a therapeutic intervention was undertaken. |
| procedure time | from start to finish of the enteroscopy | from start to finish of the enteroscopy |
| adverse events | From first day until 30 days | Adverse reactions refer to bleeding, perforation, aspiration pneumonia, acute pancreatitis and other conditions related to double-balloon enteroscopy. |
Countries
China
Outcome results
None listed