Cardiovascular Diseases
Conditions
Keywords
Nutrition, Screening, Cardiac surgery, Clincial outcomes
Brief summary
This is a nutritional screening and assessment study conducted prior to heart surgery. The nutritional status of patients will be assessed by a series of questionnaires, blood/urine biomarkers and measurement of grip strength and body composition. The investigators will then evaluate of any of the assessments are linked with clinical outcomes following surgery. For example, how long do patients stop in the intensive care unit (ICU), in hospital and how many complications patients experience. The investigators hope to use this important clinical data to understand how medical staff can identify a poor nutritional status and which patients may need nutritional support prior to surgery.
Detailed description
This is a cross sectional nutritional screening and assessment study conducted prior to cardiac surgery . The investigators will focus on comparing aspects of nutritional status with robust and validated clinical outcomes (mechanical ventilation, ICU time, hospital stay and Society of Cardiothoracic Surgery (SCTS) complications). The investigators will utilise various nutritional screening questionnaires and assessments, including routine clinical malnutrition tools (i.e. MUST, NRS), plus more nutritional quality assessments such as the NOVA ultra-processed food intake, mediterranean diet and blood biomarker panels such as the Prognostic Nutritional Index (PNI), Controlling Nutritional Status (CONUT). The investigators will also undertake a functional grip strength test and measure body composition including fat mass (FM) & fat-free mass (FFM), segmental analysis, sarcopenic obesity and visceral fat. The study will also conduct questionnaires regarding other lifestyle related factors (sleep, recent physical activity, stress, anxiety, depression) which might also influence surgical outcomes.
Interventions
BEHAVIORALNutritional Screening
To identify which nutritional screening approaches (nutritional questionnaires, biomarkers, sarcopenic obesity or grip strength are most strongly linked to surgical outcomes following cardiac surgery.
Sponsors
Hull University Teaching Hospitals NHS Trust
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
• No pre-specified inclusion criteria to ensure we recruit a representative group of patients.
Exclusion criteria
* All patients without proficiency in English that allows completion of questionnaires * Unable to provide written consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time in ICU | From ICU admission until ICU discharge, up to 30 days | The total time in hours spent in the ICU, calculated from ICU admission following cardiac surgery to ICU discharge to the general cardiology ward |
| Complications post cardiac surgery | Number of complications following cardiac surgery, up to 30 days | The number of Society of Cardio-thoracic Surgery register of complications |
| Length of Hospital Stay | From hospital admission until hospital discharge, up to 30 days | Length of hospital stay from admission to medical discharge |
Countries
United Kingdom
Contacts
CONTACTMahmoud M Loubani, MD
CONTACTJames P Hobkirk, PhD
Outcome results
None listed