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Brief Interpretation Bias Modification for Social Anxiety Disorder in Pakistani Young Adults: An Experimental Evaluation

Efficacy of Cognitive Bias Modification Itervention in Young Adult With Social Anxiety

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07406321
Acronym
BIBM-SAD-PYA
Enrollment
130
Registered
2026-02-12
Start date
2026-02-01
Completion date
2026-04-01
Last updated
2026-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interpretation Bias, Social Anxiety Disorder

Keywords

interpretation bias modification, Word-Sentence Association Paradigm, Social Anxiety Disorder, Pakistan Young Adult, Cogntive Bias Modification

Brief summary

This randomized, single-blind trial tests whether one session of interpretation bias modification reduces immediate social-evaluative anxiety and shifts interpretation bias in Pakistani university students aged 18 to 25 years with elevated social anxiety. Participants are assigned to either feedback-contingent interpretation bias modification or a structurally matched interpretation control condition. Primary and secondary outcomes are assessed before and after the intervention session using short-form state-trait anxiety measures and Word-Sentence Association Paradigm endorsement indices.

Detailed description

Social anxiety in young adults is maintained in part by a tendency to interpret ambiguous social information as threatening. The study evaluates a behavioral interpretation training procedure delivered with OpenSesame, using trial-by-trial responses to ambiguous social sentences preceded by threat or benign prime words. In the experimental arm, feedback contingently reinforces benign endorsements and threat rejections. In the control arm, exposure and timing are matched but feedback is noncontingent and presented on half of trials. The design is a parallel two-arm randomized pretest-posttest trial with participant masking to assignment. Assessment includes the 5-item state and 5-item trait short-form State-Trait Anxiety Inventory totals and Word-Sentence Association Paradigm threat and benign endorsement proportions. The mechanistic hypothesis is that feedback-consistent learning increases benign interpretations and reduces threat interpretations, which is associated with lower post-session state anxiety. The trial was conducted as part of a PhD thesis at the University of Gujrat under formal institutional approvals.

Interventions

BEHAVIORALWSAP-based interpretation bias modification

Single-session Word-Sentence Association Paradigm training with performance-contingent feedback across 220 trials in two 110-trial blocks; each block includes 70 social ambiguity trials and 40 non-social fillers. Correct feedback follows benign endorsement or threat rejection; incorrect feedback follows threat endorsement or benign rejection.

BEHAVIORALWSAP interpretation control condition

Matched Word-Sentence Association Paradigm exposure with identical stimulus timing and response demands, feedback delivered on 50 percent of trials without contingency favoring benign over threat interpretations.

Sponsors

Ather Mujitaba
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Participants are unaware of arm assignment.

Intervention model description

Parallel Assignment.

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

* age 18 to 25 years * Social Phobia Inventory score greater than 19 * at least moderate severity on the DSM-5-TR Severity Measure for Social Anxiety Disorder-Adult * able to read study materials * provides written informed consent.

Exclusion criteria

* clinically elevated depressive symptoms on Beck Depression Inventory-II at or above prespecified cutoff \[above 16\] * clinically elevated general anxiety symptoms on the Beck Anxiety Inventory at or above prespecified cutoff \[ above 20\] * current medical or psychiatric condition likely to interfere with safe or valid participation * prior participation in this trial.

Design outcomes

Primary

MeasureTime frameDescription
short version of the Spielberger State-Trait Anxiety InventoryBaseline (pre-intervention, same visit) and immediate post-intervention after the single-session training (same visit, approximately 30 to 60 minutes after intervention)The primary outcome is within-participant change in state anxiety measured with the 5-item short-form State-Trait Anxiety Inventory state subscale (STAIS-5). Items are summed to a total score, with higher scores indicating greater state anxiety. The primary comparison is the between-group difference in change score (IBM versus ICC).
Spielberger short-form State-Trait Anxiety Inventory (S-STAI)Baseline pre-intervention and immediate post-intervention in the same visit (approximately 30 to 60 minutes after training starts).Difference between post-session and baseline STAIS-5 total score; higher scores indicate greater state anxiety.

Secondary

MeasureTime frameDescription
Change in Word-Sentence Association Paradigm threat endorsement rate.Baseline pre-intervention and immediate post-intervention in the same visit.Proportion of threat word-sentence pairings endorsed as related; lower values indicate less threat-consistent interpretation. Used as interpretation bias metrices.

Countries

Pakistan

Contacts

CONTACTather mujitaba mujitaba Mujitaba, PhD Scholar
ather.mujitaba@gift.edu.pk+923297596056
PRINCIPAL_INVESTIGATORSaima Riaz Riaz, PhD

University of Gujrat

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026