Healthy Adult
Conditions
Keywords
blood flow restriction, exercise, high-intensity, rotator cuff
Brief summary
This study aims to analyze the effects of an 8-week strength training program combining different exercise intensities and blood flow restriction (BFR) conditions on safety, tolerability, muscle adaptations, and physical performance variables. Three training modalities will be compared: 1) high-intensity exercise with BFR therapy; 2) low-intensity exercise with BFR therapy; and 3) high-intensity exercise without BFR therapy. All groups will perform the same exercise modality, differing only in intensity and the application of BFR. Participants will be randomly assigned to one of the three groups and will undergo a 8-week intervention. The variables of interest will be assessed in each group for subsequent analysis and comparison.
Interventions
DEVICEHigh-intensity exercise with BFR
Three exercises: external rotation at 0°, internal rotation at 0° and elevation in the scapular plane. 4 sets (30, 15, 15, reps to fatigue) with a intensity of 70% RM and a 50% of arterial occlusion pressure. 30" rest between sets, 2' rest between exercises.
DEVICELow-intensity exercise with BFR
Three exercises: external rotation at 0°, internal rotation at 0° and elevation in the scapular plane. 4 sets (30, 15, 15, reps to fatigue) with a intensity of 30% RM and a 50% of arterial occlusion pressure. 30" rest between sets, 2' rest between exercises.
PROCEDUREHigh-intensity exercise without BFR
Three exercises: external rotation at 0°, internal rotation at 0° and elevation in the scapular plane. 4 sets (30, 15, 15, reps to fatigue) with a intensity of 70% RM and a without flow restriction application (cuff applied without pressure). 30" rest between sets, 2' rest between exercises.
Sponsors
University of Valencia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy, untrained adults * Age between 18 and 65
Exclusion criteria
* Current participation in an upper limb strength training program * Presence of comorbidities that increase cardiovascular risk (uncontrolled ischemic heart disease, uncontrolled hypertension, diabetes, etc.) * Patients with more than one thromboembolism risk factor (obesity, history of thrombosis, prolonged immobilization, recent surgery, use of contraceptives, etc.) * Current diagnosis of any pathology affecting the cervical spine, shoulder, and/or thoracic spine * History of surgery in the last year * Use of ergogenic aids or medications that affect muscle metabolism (anabolic steroids, testosterone, creatine, protein supplements, corticosteroids, chronic use of nonsteroidal anti-inflammatory drugs, etc.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Isometric rotator cuff strength | Baseline, 4 weeks and 8 weeks | Isometric rotator cuff strength measured with a dynamometer |
| Rate of perceived exertion | Periprocedural | Rate of perceived exertion (RPE) measured using the Borg scale (0-10) |
| Perceived tolerance | 8 weeks | Participant tolerance to the training protocol will be assessed at the end of the intervention using a 5-point Likert scale, ranging from very well tolerated (5), well tolerated (4), neutral (3), poorly tolerated (2), to very poorly tolerated (1). |
| Occurrence of adverse effects | Immediately after the intervention, 1 hour, 6 hours, 24 hours, 1 week | Occurrence of adverse effects (e.g., pain, delayed onset muscle soreness, sudden weakness of the trained limb, redness or swelling of the trained limb, etc.) by self-report |
| Surface electromyography | Periprocedural | Surface electromyography for the study of muscle recruitment (middle deltoid, infraspinatus, teres minor and trapezius muscles) |
| Muscle Thickness | Baseline, 4 weeks, 8 weeks | Muscle thickness of the deltoid, biceps brachii, infraspinatus, supraspinatus and subescapularis will be assessed using ultrasound imaging |
Contacts
CONTACTAdrian Escriche-Escuder, PhD
PRINCIPAL_INVESTIGATORAdrian Escriche-Escuder, PhD
University of Valencia
Outcome results
None listed