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Sustained Natural Apophyseal Glides With and Without Integrated Neuromuscular Inhibition Technique in Neck Pain

Effects of Sustained Natural Apophyseal Glides With and Without Integrated Neuromuscular Inhibition Technique on Pain, Range of Motion, and Function in Patients With Chronic Mechanical Neck Pain

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07403279
Enrollment
44
Registered
2026-02-11
Start date
2025-08-18
Completion date
2025-11-18
Last updated
2026-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Mechanical Neck Pain

Keywords

Integrated Neuromuscular Inhibition Technique, Neck pain, Range of Motion, Sustained Natural Apophyseal Glides, Trigger points

Brief summary

The study was conducted to determine the effects of Sustained Natural Apophysial Glide with and without Integrated Neuromuscular Inhibition Technique on pain, range of motion and function in patients with chronic mechanical neck pain

Interventions

SNAGs were applied in three sets, with repetitions progressively increased from 6 to 10 over a period of four weeks, administered three times per week.

OTHERIntegrated Neuromuscular Inhibition Technique

The integrated neuromuscular inhibition technique comprised three steps: ischemic compression, strain-counterstrain technique, and muscle energy technique. The technique was applied to the upper trapezius, levator scapulae, sternocleidomastoid, and splenius capitis muscles. Muscle selection was based on palpatory examination performed prior to each treatment session. Each treatment session lasted 10 minutes, during which all three steps were repeated three times within a single session. The intervention was delivered three times per week for four weeks, resulting in a total of 12 treatment sessions.

Standardized physiotherapy included the application of an electrical hot pack at moderate intensity for 10 minutes. Transcutaneous electrical nerve stimulation (TENS) delivered in continuous mode at a frequency of 100 Hz for 15 minutes. Passive stretching was performed for cervical muscles prone to tightness, including the levator scapulae, sternocleidomastoid, upper trapezius, and scalene muscles, with a 30-second hold, three sets of ten repetitions, and a one-minute rest between sets. Scapular stabilization exercises, comprising shoulder shrugging and scapular retraction, were performed for 15 repetitions with a 6-second hold. Neck isometric exercises were repeated ten times with a 6-second hold. Cervical stabilization exercises were performed in two sets of ten repetitions per session, with each repetition held for ten seconds, a forty-second rest between repetitions, and a two-minute rest between sets.

Sponsors

Riphah International University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* Age ranged from 18 to 45 years and both genders. * Patient having neck-pain symptoms for more than 3 months duration. * Spurling test, distraction test, upper limb tension test and shoulder abduction test negative upon assessment. * The participants should have MTrPs in any one of these following cervical muscles which include levator scapulae, upper trapezius, splenius capitis and sternocleidomastoid muscles which may be active or latent. * A score greater than twenty percent on NDI. * Jump Sign when pressure is applied. * Positive Simons criteria which contains following these 5 characteristics :(1) Pain on palpation (2) pain that is radiating (3) Tightened cord like structure in muscle fiber that is detectable upon palpation(4) Reduced Flexibility of that muscle (5) 'twitching response' on needling. * Participants who described pain which is felt between spinous process of 1st thoracic vertebrae and superior nuchal line in posterior or posterolateral part of neck

Exclusion criteria

* Recent fracture, trauma (whiplash injury) and surgery in and around the shoulder and neck * Neural disorders due to prolapsed intervertebral disc * Carcinoma, Heart diseases, Metabolic disease in bone and joints * Patients having history of osteoporosis, prolong steroid and analgesics use * Unstable spine and open sores, Localized infection in neck * Vertebrobasilar insufficiency. * Cervical radiculopathy and myelopathy

Design outcomes

Primary

MeasureTime frameDescription
Numeric Pain Rating ScaleFrom enrollment to end of treatment at 4th weeksNumeric Pain Rating Scale is utilized to evaluate pain.This is a scale between 0 and 10 where 0 denotes no pain and 10 denotes the worst pain whereas 1-3 denotes mild pain 4-6 denotes moderate pain and 7-10 denotes severe pain.

Secondary

MeasureTime frameDescription
Neck Disability IndexFrom enrollment to the end of treatment at 4th weeksThe Neck Disability Index is a self-reported questionnaire used to assess neck-related functional disability. It consists of 10 items addressing pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleeping, and recreation. Each item is scored on a 6-point scale (0-5), with a total score ranging from 0 to 50, where higher scores indicate greater disability. Scores are categorized as no disability (0-4), mild disability (5-14), moderate disability (15-24), severe disability (25-34), and complete disability (≥35).
Range of Motion Cervical Spine (Flexion)From enrollment to the end of treatment at 4th week.Changes in cervical spine flexion range of motion at baseline and 4th week of intervention was measured using goniometer
Range of Motion Cervical Spine (Extension)From enrollment to the end of treatment at 4th weekChanges in cervical spine extension range of motion at baseline and 4th week of intervention was measured using goniometer.
Range of Motion Cervical Spine (Lateral Flexion) Right SideFrom enrollment to the end of treatment at 4th weekChanges in cervical spine lateral flexion on right side range of motion at baseline and 4th week of intervention was measured using goniometer.
Range of Motion Cervical Spine (Lateral Flexion) Left SideFrom enrollment to the end of treatment at 4th weekChanges in cervical spine lateral flexion on left side range of motion at baseline and 4th week of intervention was measured using goniometer.
Range of Motion Cervical Spine (Rotation) Right SideFrom enrollment to the end of treatment at 4th weekChanges in cervical spine rotation on right side range of motion at baseline and 4th week of intervention was measured using goniometer
Range of Motion Cervical Spine (Rotation) Left SideFrom enrollment to the end of treatment at 4th weekChanges in cervical spine rotation on left side range of motion at baseline and 4th week of intervention was measured using goniometer

Countries

Pakistan

Contacts

PRINCIPAL_INVESTIGATORSyed Shakil ur Rehman, Ph.D

Riphah International Universirty

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026