Dexamethasone, Bupivacaine, Upper Limb Surgery
Conditions
Keywords
dexamethasone,Bupivacaine,Analgesia,supraclavicular block
Brief summary
* SCBPBs provides optimal conditions for procedures performed below the mid-upper arm (elbow, forearm, wrist, hand) due to its high success rate and ease of access. * Dexamethasone, when administered perineurally as an adjuvant for a supraclavicular block, demonstrated early onset of sensory and motor block, a prolonged duration of sensory and motor block, and a lower number of rescue analgesics as compared to bupivacaine alone. * A combination of dexamethasone and bupivacaine is paramount in adult orthopeadic patient to enhance the efficacy of pain management under ultrasound-guided supraclavicular brachial plexus block.
Interventions
Adding 8 mg of dexamethasone to bupivacaine for ultrasound-guided supraclavicular block
Sponsors
Arsi University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Aged 18-60 years with ASA I and II who were scheduled for elective elbow, forearm, or hand surgery under ultrasound-guided supraclavicular block.
Exclusion criteria
Patients who refused, used local anaesthetics other than bupivacaine, had multiple traumas, addition of another additive, bleeding disorders, patients diagnosed with chronic pain, cancer pain, local infection at the injection site, history of local anaesthetic allergy, patients with anxiety, and inability to comprehend or use the pain rating scale
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The onset of sensory and motor blockade, and the duration of sensory and motor blockade in minutes. | with in the first 24hrs after procedure | 1. The onset of sensory: the period between injecting a study solution and losing sensation to a pinprick at every nerve distribution 2. The onset of motor block: The duration between the injection of the study solution and paresis in every nerve distribution. 3. duration of sensory: the period between the onset of a sensory block and the complete restoration of sensation. 4. Duration of motor block: the period between the onset of a motor block and the complete restoration of motor function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pain score by a visual analogue scale | with in the first 24 hrs after procedure | This assesses behavioural or subjective phenomena by having the participant choose an alternative from a gradient ranging from 0 = (no pain) to 100 = worst possible pain. Based on the VAS score, 0-20 mm = no pain; 21-40 mm = mild pain; 41-60 mm = moderate pain; 61-80 mm = severe pain; and 81-100 mm = the worst pain imaginable |
| First analgesic request time | With in the first 24 hrs after surgery | The first postoperative period, when patients require pain treatment if the visual analogue score is\>4 |
Countries
Ethiopia
Outcome results
None listed