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Effects of Powerlifting-Based Training in Athletes

The Effects of Powerlifting-Based Training on Hormonal, Metabolic, and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07398248
Acronym
PLBT-ATH
Enrollment
30
Registered
2026-02-09
Start date
2025-01-10
Completion date
2025-10-15
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hormonal Response, Metabolic Parameters, Physical Fitness

Keywords

Powerlifting, Strength Training, Basketball

Brief summary

This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.

Detailed description

This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines. The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.

Interventions

OTHERPowerlifting-Based Training

Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision.

OTHERUsual Basketball Training

Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises.

OTHERBlood Sampling and Laboratory Analysis

Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.

Sponsors

Ramazan Erdoğan
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 24 Years
Healthy volunteers
Yes

Inclusion criteria

* Male basketball players aged 18 to 24 years * At least two years of regular sports experience * Actively participating in basketball training and competition * Voluntary participation with written informed consent

Exclusion criteria

* History of musculoskeletal injury or surgery within the last six months * Presence of chronic disease or metabolic disorder * Use of performance-enhancing drugs or hormonal supplements * Participation in another structured training program during the study period

Design outcomes

Primary

MeasureTime frameDescription
Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

Secondary

MeasureTime frameDescription
Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting serum insulin concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).
Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention fasting blood glucose concentrations, measured from venous blood samples using an automated biochemical analyzer.
Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention total cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention low-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention high-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.
Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL)Baseline and post-intervention (8 weeks)Mean difference between baseline and post-intervention triglyceride concentrations, measured from venous blood samples using an automated biochemical analyzer.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 3, 2026