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Necessity of Post-operative Eye Drops

Safety of Retina Surgery Without Postoperative Eye Drops

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07396831
Enrollment
48
Registered
2026-02-09
Start date
2024-04-09
Completion date
2025-12-22
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection Prophylaxis, Pars Plana Vitrectomy, Scleral Buckling, Surgical Outcomes

Keywords

Pars plana vitrectomy, Scleral buckling, Infection prophylaxis, Topical antibiotics

Brief summary

The goal of this clinical study is to determine if antibiotic eye drops are needed after retinal surgery to prevent infection. Currently, patients are prescribed antibiotic eye drops to use for several weeks after they undergo retina surgery. The main question that we are trying to answer is: \- Are postoperative eye drops necessary to prevent eye infections after retina surgery? Patients will still receive steroid drops after their surgery to control inflammation. Additionally, patients will have regular follow up with their eye surgeon to monitor for the signs and symptoms of eye infection.

Interventions

None listed

Sponsors

Loma Linda University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients undergoing Pars plana vitrectomy and/or scleral buckling

Exclusion criteria

* Patients younger than 18 * Patients undergoing Pars plana vitrectomy for endophthalmitis * Patients having combined intraocular lens and vitrectomy surgery * Patients that received a cornea scrape during surgery

Design outcomes

Primary

MeasureTime frameDescription
Presence of endophthalmitis30 daysThe primary outcome of this study is the presence of endophthalmitis 30 days after pars plana vitrectomy and/or scleral buckling without the use of post-operative antibiotics.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORBailey Shen, Doctor of Medicine

Loma Linda University Eye Institute

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026