Endocrine-exocrine Functions and Prognosis After Pancreatectomy

The Analysis of Endocrine-exocrine Functions and Prognosis After Pancreatectomy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07396662

Enrollment

3500

Registered

2026-02-09

Start date

2016-01-01

Completion date

2034-12-31

Last updated

2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic Neoplasm

Brief summary

Pancreatic diseases often require surgery or invasive procedures to provide a chance for a cure. However, due to the pancreas's unique anatomical structure, its relative position to adjacent organs, and its dual endocrine and exocrine functions, the complexity of surgery is increased, impacting the patient's postoperative quality of life. Therefore, this project aims to retrospectively collect basic data, preoperative and postoperative blood tests (blood cell counts, biochemistry, tumor markers, glucose-related, lipid-related), and preoperative and postoperative imaging examinations (CT, MRI, Ultrasound, PET scan, Endoscopy, etc.) of patients who underwent pancreatic surgery at our hospital. We aim to compare whether surgical methods, lesion margin clearance rates, and postoperative remnant pancreatic volume affect the patient's endocrine function, exocrine function, quality of life, and disease prognosis. This analysis is intended to understand the indications, surgery-related factors, and prognosis for patients planning to undergo pancreatic surgery, with the expectation of providing more diverse and specific treatment recommendations for patients with pancreatic diseases in the future

Interventions

PROCEDUREpancreatectomy

all procedures demanding pancreatic parenchyma transaction

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 75 Years

Healthy volunteers

Inclusion criteria

* All patients scheduled for pancreatectomy

Exclusion criteria

* Age under 20 years or older than 75 years; Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
postoperative pancreatic endocrine-exocrine functions	6 months after pancreatectomy	1. Pancreatic endocrine function will be measured by incidence of appearance of new-onset or aggravated DM after operation. 2. pancreatic exocrine function will be measured by incidence of appearance of steatorrhea which can be alleviated by replacement of digestive enzyme.

Countries

Taiwan

Contacts

CONTACTYu Wen Tien, Ph.D.

ywtien5106@ntu.edu.tw0972651427

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026