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Comparison of Quadratus Lumborum Block Types in Open Gynecologic Surgery

A Prospective Observational Comparison of Quadratus Lumborum Block Techniques in Gynecologic Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07395440
Enrollment
68
Registered
2026-02-09
Start date
2025-04-01
Completion date
2025-05-15
Last updated
2026-02-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pain Management, Gynecologic Surgical Procedures, Quadratus Lumborum Block

Keywords

quadratus lumborum block, open gynecological operations, acute pain

Brief summary

This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Type 2 blocks on postoperative acute pain in gynecological operations performed with a Pfannenstiel incision.

Detailed description

This prospective observational study was conducted to observe and analyze postoperative acute pain outcomes in patients undergoing open gynecologic surgery with a Pfannenstiel incision. The study included patients who received quadratus lumborum block (QLB) techniques as part of routine perioperative analgesic management. Quadratus lumborum blocks were performed using ultrasound guidance according to standard clinical practice. The block was administered with the patient in the lateral position, and a high-frequency linear ultrasound transducer was used to identify the quadratus lumborum muscle and surrounding anatomical structures. For Quadratus Lumborum Type 1 (lateral) block, local anesthetic was injected at the anterolateral border of the quadratus lumborum muscle. For Quadratus Lumborum Type 2 (posterior) block, local anesthetic was deposited posterior to the quadratus lumborum muscle, within the thoracolumbar fascial plane. The selection of Quadratus Lumborum Type 1 or Type 2 block was determined solely by the attending anesthesiologist based on routine clinical considerations, surgical characteristics, and patient-related factors. No intervention or regional analgesia technique was assigned by the investigators for the purpose of this study, and study participation did not influence anesthetic management. Participants would have received the same anesthetic and regional analgesia techniques in the same manner and intensity regardless of study enrollment. Postoperative acute pain outcomes were prospectively collected and analyzed between predefined exposure groups according to the routinely applied quadratus lumborum block technique. The investigators did not modify clinical practice, dosing, timing, or performance of regional anesthesia. All anesthetic and analgesic interventions were provided as part of standard medical care. This study was approved by the local ethics committee as an observational study and was conducted in accordance with institutional standards of care.

Interventions

None listed

Sponsors

Ankara Etlik City Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* ASA I-III * Female patients aged 18-80 * Cases undergoing open myomectomy and total abdominal hysterectomy

Exclusion criteria

* Those who do not want a block * Patients who are allergic to local anesthetics * Patients with coagulopathy * Pregnancy * Previous surgery in the area where the block will be applied

Design outcomes

Primary

MeasureTime frameDescription
Reduction of opioid requirement in patients undergoing open myomectomy and total abdominal hysterectomyfrom april to mayIt investigates the effectiveness of quadratus lumborum 1 block alone in acute pain, compared to quadratus lumborum 1 and 2 blocks applied together in patients undergoing open myomectomy and total abdominal hysterectomy.

Secondary

MeasureTime frameDescription
no need for additional analgesiafrom 1 may to 15 maythe first postoperative analgesic consumption in patients undergoing open myomectomy and total abdominal hysterectomy.

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORKADİR T ETİKCAN, MEDİCAL DOCTOR

ANKARA ETLİK CİTY HOSPİTAL

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026