Musculoskeletal Pain
Conditions
Brief summary
In this pilot study, the investigators aim to compare two short-term pain relief methods administered over the course of 6 days in the setting of acute musculoskeletal (MSK) pain: 1. Methylprednisolone((Medrol)dose pack- standard taper per dose pack instructions 2. Standard of Care (SOC) which includes a combination of Acetaminophen (Tylenol)+Ibuprofen (Motrin) The investigators are interested in studying pain relief regimens for acute injury of any body part among an adult orthopaedic urgent care population.
Interventions
DRUGMethylprednisolone 4Mg Tab
Participants follow standard 6- day taper dosing schedule.
Participants follow a 6- day taper dosing schedule.
Participants follow a 6- day taper dosing schedule.
Sponsors
State University of New York at Buffalo
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults 18+ * Able to answer survey questions in English * MSK pain \> 3 on the VAS scale in any body part * Invited to participate by and enrolling clinician
Exclusion criteria
* \> 2 weeks from pain onset * Fractures * Active infections * Anaphylactic reaction to either medication (Oral Steroids, Ibuprofen, and/or Acetaminophen) * Currently taking anti-platelet agents (aspirin \</= 100/mg a day, clopidogrel, etc.) * Chronic Kidney Disease Stage 3 or worse * Uncontrolled diabetes (A1C above 9) * Currently taking oral anti-coagulants * History of bleeding ulcer * Cirrhosis * Taking daily prednisone * Chronic pain syndrome * Chronic pain medication (gabapentin, Lyrica, narcotics, etc.) * Pregnant Patients * Worker's Compensation Patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Pain | 1 week, 1 month | Pain as self-reported by the patient, following pain medication treatment for an acute musculoskeletal (MSK) injury as measured with the Visual Analog Scale (VAS) where 0 is no pain at all and 10 is the worst pain imaginable. Lower scores indicate less pain. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Function | 1 week, 1 month | Function as self-reported by the patient following pain medication treatment for an acute musculoskeletal (MSK) injury as measured with the musculoskeletal health questionnaire (MSK-HQ) scale which sums 14 health domains on a 5-point scale from 4 being not at all and 0 to very severe. Higher scores indicate better overall MSK health. |
Countries
United States
Outcome results
None listed