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Partial Wrist Denervation in Comminuted Articular Distal Radius Fractures

Partial Wrist Denervation in Comminuted Articular Distal Radius Fractures

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07393061
Enrollment
56
Registered
2026-02-06
Start date
2026-01-01
Completion date
2027-01-01
Last updated
2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture Disatl Radius, Parial Denervation

Keywords

parital denervation, comminuted distal radius fractures, chronic wrist pain

Brief summary

the aim of Partial Wrist Denervation in Comminuted articular Distal Radius Fractures is to decrease incidence of chronic wrist pain follwing this type of fracture

Detailed description

Distal radius fractures represent the most common fractures in adults showing an overall prevalence of 17.5 % with respect to all fractures. partial wrist denervation is an adjunctive procedure performed during initial fracture fixation to mitigate chronic pain by interrupting sensory innervation to the wrist joint. It targets the anterior interosseous nerve (AIN) and posterior interosseous nerve (PIN), which convey nociceptive signals from the radiocarpal and midcarpal joints. Comminuted intra-articular distal radius fractures (AO/OTA Type C2/C3) often lead to post-traumatic arthritis due to articular incongruity and capsular damage. Denervation at the index procedure may reduce central sensitization and chronic pain by resecting afferent pain fibers, potentially improving postoperative rehabilitation and functional outcomes. Acute comminuted intra-articular distal radius fractures (AO/OTA C2/C3) with high risk of post-traumatic arthritis (e.g., articular step-off \>2 mm, severe fragmentation). * Active individuals seeking motion preservation, those with high functional demands (e.g., athletes, laborers), or patients preferring a less invasive option than salvage procedures. * Adjunct to primary fixation: Performed concurrently with volar locking plate (VLP) or dorsal plating.

Interventions

PROCEDUREPartial Wrist Denervation in Comminuted articular Distal Radius Fractures

Partial Wrist Denervation in Comminuted articular Distal Radius Fractures through sme approach of the surgery

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

observational

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Age from 18 * Fracture Pattern: Acute, comminuted intra-articular distal radius fractures (AO/OTA Type C2 or C3). * Surgical Context: Procedure performed as a primary adjunct during initial open reduction and internal fixation (ORIF).

Exclusion criteria

Active local infection over the surgical site. * Compromised soft tissue envelope that precludes safe dissection. * Vascular injury or compromise requiring repair. * Pre-existing neurological deficit (e.g., complex regional pain syndrome, major peripheral nerve injury).

Design outcomes

Primary

MeasureTime frameDescription
The end results PAIN will be assessed according to mayo clinc wrist score2 weeks, 6 weeks, 3 months, 6 months..and 1 yearmayo clinc wrist score its a clincal reported outcome measure designed to assess function and pain of the wrist follwing surgery the score is bassed on 100 points divided into four equally weighted categories the final score places the wrist into outcome category total score 90/100 is excellent while below 65 is poor

Countries

Egypt

Contacts

STUDY_DIRECTORwalyd ryad saleh, professor of orthopedics

Assiut University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026