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Optimisation of the Blood Culture Pathway Utilising Behaviour Change

Optimisation of the Blood Culture Pathway Utilising Behaviour Change

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07392684
Enrollment
24
Registered
2026-02-06
Start date
2025-10-01
Completion date
2026-09-30
Last updated
2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Culture, Microbiology

Brief summary

Blood culture (BC) is the gold standard for the definitive diagnosis of bacteraemia, providing the opportunity to recover and identify the causative organism, and optimize subsequent antimicrobial treatment. Detection of bacteraemia is critical for the management of sepsis. This study aims to examine the performance of the blood culture pathway in Gloucestershire Hospitals Trust using data analysis, questionnaires and focus groups. . Information collected will be used to design interventions that could be used to optimise the blood culture pathway

Detailed description

Retrospective data collection relating to the blood volume collected and time to incubation of adult blood culture sets (adult sets comprises of both aerobic and anaerobic blood culture bottle) received in the microbiology laboratory, between February 2023 and April 2024. These samples are routinely collected as standard of care and not for the purpose of this research. Staff members that collect adult blood cultures within the Trust (nurses, Physician's associates and doctors) will be invited to volunteer for the study. Staff members will participate by completing the questionnaire and/or attending focus groups.

Interventions

None listed

Sponsors

Gloucestershire Hospitals NHS Foundation Trust
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Secondary data: \- adult blood culture sets received in the microbiology laboratory, between February 2023 and April 2024. Staff member participants \- Staff members that collect adult blood cultures within the Trust

Exclusion criteria

Secondary data: * paediatric blood culture samples * samples where volume, collection and/or time to incubation data are not recorded on laboratory system and/or blood culture analyser

Design outcomes

Primary

MeasureTime frameDescription
Compliance to optimal blood culture (BC) vol (8-10 mls per bottle).Retrospective data collection from period February 2023 to April 2024.Volume of blood cultures measured in ml.
Compliance to 4- hour time target to incubation of blood culture from collection.Retrospective data collection from period February 2023 to April 2024Time taken from collection of blood culture to incubation in the laboratory, recorded in hours and minutes
Time from collection of blood cultures to targeted antibiotics, hours and minutesRetrospective data collection from period February 2023 to April 2024.Measurement of time (hours, minutes) from time of blood culture collection to time of targeted antibiotic prescribing
Staff experiences related to taking blood culturesApproximately 10 minutes to complete electronic questionnaire. Attendance at single FOCUS group at agreed time.Staff experiences using questionnaires and focus group discussions exploring facilitators and barriers relating to blood culture collection . Staff members will participate by completing the questionnaire and/or attending focus groups.

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026