Role of (Saline- Glycerin) Rectal Enema in Treatment of Fecal Incontinence in Children

Status

Not yet recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07392203

Enrollment

Registered

2026-02-06

Start date

2026-02-15

Completion date

2026-08-30

Last updated

2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorectal Malformation

Brief summary

Using saline glycerin mixture once daily in children with fecal incontinence to reach aclean child without fecal accidents the next day.

Detailed description

Child lies on Lt lateral position. Foley catheter inserted to thr rectum and inflated Instillation of saline glycerin mixture. Child hold it for 15 minutes Foley catheter removed Child stay in bathroom for 45 min

Interventions

PROCEDURERectal enema using saline and glycerin mixture once daily

Rectal enema using saline \& glycerin for treatment of fecal incontinence in children

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

3 Years to 16 Years

Healthy volunteers

Inclusion criteria

InclusioChildren ≥3 and ≤16 years with Fecal incontinence (≥1 episode/week) due to corrected anorectal malformation (ARM), Hirschsprung disease after pull-through, perineal trauma, spinal anomalies/neurogenic bowel, or functional constipation with overflow incontinence. Ability to participate in a structured bowel-management regimen at home. Caregiver availability for training and daily administration. n Criteria: \- Age \<3 years. symptomatic anal stricture, or other anatomic issues requiring surgical correction before bowel management. Current enterocolitis, Active proctitis, painful fissure with bleeding, or severe perianal dermatitis precluding safe catheterization. Chronic kidney disease, unstable cardiac disease, or known electrolyte imbalance. Hypersensitivity/intolerance to glycerin; prior severe reaction to enemas. Stoma in situ or ACE dependence (separate pathway).

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
Proportion of clean days (no stool accidents) during days 7-14 of titration and at week 4.	Follow up after 4 weeks and after 12 weeks

Countries

Egypt

Contacts

CONTACTSuzan Ali Mohammed, Resident of pediatric surgery

an4562195@gmail.com01143847284

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026