Healthy Adult, Multiple Sclerosis
Conditions
Brief summary
The study aims to investigate specific ambulation patterns characteristic of the quality of gait in people with MS (pwMS)
Interventions
None listed
Sponsors
SYSNAV
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
For people living with multiple sclerosis (pwMS): 1. Age at inclusion between =18 and =65 years old 2. Signed informed consent and ability to comply with study and follow-up. 3. Confirmed MS diagnosis according to McDonald criteria (2017) 4. Expanded Disability Status Scale EDSS = 6 5. Stable treatment for 2 months before inclusion (for both disease modifying and symptomatic therapies) 6. Ability and willingness to participate in and comply with all study procedures defined in the protocol 7. Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category For Healthy volunteers : 1. Age at inclusion between =18 and =65 years old 2. Signed informed consent and ability to comply with study and follow-up. 3. Ability and willingness to participate in and comply with all study procedures defined in the protocol 4. Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category
Exclusion criteria
For pwMS: 1. Participants with a relapse within the past 3 months before the inclusion 2. Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator 3. Past or present pathology other than MS or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator 4. Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent. For healthy volunteers (HV): 1. Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator 2. Past or present pathology or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator 3. Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| description of ambulation pattern in controlled environment in people living with multiple sclerosis (pwMS) with different disease severities | enrollment | Measurement of daily life-like activity movements by Optical Motion Capture, pressure sensitive walkway and wearable sensors |
Countries
France
Contacts
CONTACTFerial Toumi
PRINCIPAL_INVESTIGATORPatrick Vermersch
CHU Lille
Outcome results
None listed