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Ultrasound Predictors of Difficult Airway in Adults

Investigation of Ultrasonographic Predictors of Difficult Intubation and Difficult Mask Ventilation in Adult Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07383610
Enrollment
400
Registered
2026-02-03
Start date
2023-10-01
Completion date
2024-10-01
Last updated
2026-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Difficult Airway, Difficult Intubation, Difficult Mask Ventilation

Keywords

Airway Ultrasonography, Ultrasound, Difficult Airway Prediction, Anesthesia

Brief summary

Difficult airway management is a major cause of perioperative complications. Standard bedside airway assessment tests may have limited ability to predict difficult intubation and difficult mask ventilation. This prospective observational study aims to evaluate whether preoperative ultrasound measurements of airway structures (such as skin-to-epiglottis distance, tongue thickness, and pre-epiglottic space) can predict difficult intubation and difficult mask ventilation in adult patients undergoing surgery under general anesthesia.

Detailed description

This prospective observational cohort study was conducted to evaluate the predictive value of preoperative ultrasonographic airway measurements for difficult intubation and difficult mask ventilation in adult patients undergoing elective surgery under general anesthesia. A total of 400 patients aged 18-70 years with ASA physical status I-III were included. Before induction of anesthesia, standard clinical airway assessment tests were recorded, and ultrasound measurements were performed to assess airway-related anatomical structures. Ultrasonographic parameters included skin-to-epiglottis distance, skin-to-thyroid cartilage distance, thyroid cartilage-to-epiglottis distance, pre-epiglottic space depth, tongue thickness, and hyomental distance measurements. Intraoperatively, mask ventilation and intubation conditions were documented. Difficult intubation was defined as requiring two or more intubation attempts. Difficult mask ventilation was defined as the need for two-handed mask ventilation or inability to ventilate adequately using a face mask. The primary objective was to determine the association between ultrasonographic measurements and difficult intubation

Interventions

None listed

Sponsors

Kutahya Health Sciences University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 18-70 years ASA physical status I-III Elective surgery under general anesthesia requiring orotracheal intubation Written informed consent

Exclusion criteria

* Refusal to participate Emergency surgery Pregnancy Known upper airway pathology or previous airway surgery Restricted mouth opening (\<3 cm) Cervical spine instability or significant limitation of neck mobility Morbid obesity (BMI ≥40 kg/m²) Obstructive upper airway masses (e.g., head and neck tumors) Prior neck radiotherapy Clinically relevant neck masses Major facial/mandibular trauma or craniofacial anomalies

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants with Difficult IntubationDuring induction of anesthesia (intraoperative)Difficult intubation was defined as requiring two or more intubation attempts (≥2 attempts) during induction of general anesthesia.
Number of Participants with Difficult Mask VentilationDuring induction of anesthesia (intraoperative)Difficult mask ventilation was defined as the need for two-handed mask ventilation or inability to ventilate adequately using a face mask

Countries

Turkey (Türkiye)

Contacts

PRINCIPAL_INVESTIGATORSerkan Telli, MD

Kutahya Health Sciences University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026