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Investigation of Skeletally Anchored Expansion of the Maxilla

Investigation of the Functional, Aesthetic, and Quality-of-life Effects of Combined Surgical-orthodontic Treatment

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07383376
Enrollment
90
Registered
2026-02-03
Start date
2025-01-06
Completion date
2025-11-13
Last updated
2026-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatal Expansion Technique

Keywords

maxillary expansion, orthodontics, occlusion

Brief summary

This study aims to compare two different methods for maxillary expansion in adult patients with transverse maxillary deficiency. Participants will receive either miniscrew-assisted rapid palatal expansion (MARPE-MICRO-4). We want to compare the surgically assisted rapid palatal expansion (SARPE) and the non surgical/conservative method. Clinical (3D scans of the upper jaws) measurements will be used to evaluate skeletal expansion and stability over time. Approximately 90 adult patients will be included and followed for 12 months. The results of this study may help clinicians choose the most appropriate treatment method for adult maxillary expansion.

Interventions

DEVICEMARPE

Miniscrew-assisted rapid palatal expander (MARPE)

PROCEDURESARME

Surgically assisted rapid palatal expansion (SARPE).

Sponsors

Semmelweis University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

PICO

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Presence of transverse maxillary deficiency requiring maxillary expansion * Indication for either non-surgical (MARPE) or surgically assisted (SARPE) maxillary expansion * Permanent dentition * Ability to understand the study procedures and provide informed consent

Exclusion criteria

* Previous maxillary expansion treatment * Craniofacial syndromes or cleft lip/palate * Severe periodontal disease * Active oral infection * Systemic conditions affecting bone metabolism * Pregnancy or breastfeeding * Inability to comply with study procedures or follow-up visits

Design outcomes

Primary

MeasureTime frameDescription
Skeletal maxillary expansion measured with 3D scansBaseline to 6 months after completion of maxillary expansion.Changes in intermolar and intercanine width will be measured on digital dental models.

Secondary

MeasureTime frameDescription
Buccal tipping of posterior teeth measured on 3D digital modelsBaseline to 6 months after completion of maxillary expansionBuccal tipping of posterior teeth will be assessed using 3D digital dental models by measuring changes in crown inclination of maxillary premolars and molars before treatment and after completion of maxillary expansion.

Countries

Hungary

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 27, 2026