High Velocity Nasal Insufflation, Simple Oxygen, Weaning Criteria
Conditions
Brief summary
A randomized clinical trial about predictors of successful extubation of pediatric patients from mechanical ventilation either on High Velocity Nasal Insufflation or simple nasal oxygen and comparing the outcome
Detailed description
A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or re-intubation within 48 hours, presence of respiratory distress or stridor post extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.
Interventions
DEVICEComparing the outcome of pediatric patients after successful weaning on either High Velocity Nasal Insufflation or simple oxygen
A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or re-intubation within 48 hours, presence of respiratory distress or stridor post extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.
DEVICEcomparing High Velocity Nasal Insufflation to simple oxygen after successful weaning of pediatric patients
A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or re-intubation within 48 hours, presence of respiratory distress or stridor post extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Intervention model description
comparing the outcome between High Velocity Nasal Insufflation and simple oxygen after successful weaning from mechanical ventilation
Eligibility
Sex/Gender
ALL
Age
2 Months to 13 Years
Healthy volunteers
No
Inclusion criteria
* Age between 2 months and 13 years old with minimum weight 4kg * Both sexes * Patients on mechanical ventilation for at least 24 hours for any indication
Exclusion criteria
* Patients not ready for weaning from mechanical ventilation * Contraindications to use of High velocity nasal insufflation * Prolonged mechanical ventilation for more than 21 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| comparing the need for reintubation within 48 hours afterr extubation using High Velocity Nasal Insufflation versus simple oxygen | 48 hours | Successful extubation with no need for reintubation within 48 hours among pediatric ICU patients in those using High Velocity Nasal Insufflation versus simple oxygen |
Countries
Egypt
Contacts
CONTACTSherin T. Fayez Ali, PICU doctor
PRINCIPAL_INVESTIGATORCairo University Cairo University
Cairo University
Outcome results
None listed